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非综合征性唇裂和/或腭裂:涉及牙齿异常的多中心研究。

Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved.

作者信息

Menezes Carlos, de Arruda José-Alcides, Silva Leni-Verônica, Monteiro João-Luiz, Caribé Pérola, Álvares Pamella, Almeida Maria-Cristina, Coelli José-Carlos, Goldemberg Fernanda, Silveira Marcia, Sobral Ana-Paula, Bueno Daniela-Franco

机构信息

Institute of Teaching and Research of Hospital Sírio Libanês, São Paulo, SP, Brazil.

Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

J Clin Exp Dent. 2018 Aug 1;10(8):e746-e750. doi: 10.4317/jced.54926. eCollection 2018 Aug.


DOI:10.4317/jced.54926
PMID:30305871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6174020/
Abstract

BACKGROUND: Nonsyndromic cleft lip and/or palate (NSCL/P) is the most common craniofacial malformation. Due to the anatomical defect present in the alveolar process, these patients tend to exhibit more dental anomalies. The aim of this study was to identify the prevalence of dental anomalies in patients with NSCL/P by obtaining orthodontic documentation from Brazilian Centers for cleft lip and palate treatment. MATERIAL AND METHODS: A retrospective analysis (2000-2014) was conducted on orthodontic archives, radiographs and medical records of NSCL/P of 524 patients under orthodontic treatment. Panoramic radiographs and intra-oral photographs were examined to identify these anomalies. Categorical variables were expressed in terms of frequencies and percentages and analyzed using the Chi-Square test. The level of significance was set at ≤0.05 in all analyses. RESULTS: Approximately 83.3% of the individuals had at least one dental anomaly. Tooth agenesis was the most common abnormality found in those patients (87.8%) (<0.001). Also, the largest number of dental anomalies was detected in the group of unilateral left clefts. The prevalence of dental anomalies in the present sample of NSCL/P patients was high and reached the highest levels in patients with alveolar bone clefts. CONCLUSIONS: This study describes the most common dental anomalies observed in patients with NSCL/P. These abnormalities can cause significant problems that may be solved or minimized by early diagnosis and treatment. Cleft lip and/or palate, dental care for children, epidemiology, craniofacial abnormalities.

摘要

背景:非综合征性唇腭裂(NSCL/P)是最常见的颅面畸形。由于牙槽突存在解剖缺陷,这些患者往往表现出更多的牙齿异常。本研究的目的是通过获取巴西唇腭裂治疗中心的正畸记录,确定NSCL/P患者牙齿异常的患病率。 材料与方法:对524例接受正畸治疗的NSCL/P患者的正畸档案、X光片和病历进行回顾性分析(2000 - 2014年)。通过检查全景X光片和口腔内照片来识别这些异常。分类变量以频率和百分比表示,并使用卡方检验进行分析。所有分析的显著性水平设定为≤0.05。 结果:约83.3%的个体至少有一项牙齿异常。牙齿缺失是这些患者中最常见的异常情况(87.8%)(<0.001)。此外,在单侧左侧腭裂组中检测到的牙齿异常数量最多。本NSCL/P患者样本中牙齿异常的患病率很高,在牙槽骨腭裂患者中达到最高水平。 结论:本研究描述了NSCL/P患者中观察到的最常见牙齿异常。这些异常可能会导致严重问题,通过早期诊断和治疗可以解决或使其最小化。唇腭裂、儿童牙科护理、流行病学、颅面异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146e/6174020/e97aa10484d1/jced-10-e746-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146e/6174020/eb22014e2544/jced-10-e746-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146e/6174020/e97aa10484d1/jced-10-e746-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146e/6174020/eb22014e2544/jced-10-e746-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146e/6174020/e97aa10484d1/jced-10-e746-g002.jpg

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[1]
Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved.

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引用本文的文献

[1]
Unilateral cleft lip and palate patients present cranial base modifications: a cross-sectional study.

Braz Oral Res. 2025-1-13

[2]
β-Tricalcium Phosphate as Alveolar Bone Grafting in Cleft Lip/Palate: A Systematic Review.

Dent J (Basel). 2023-10-7

[3]
Current Concepts and Challenges in the Treatment of Cleft Lip and Palate Patients-A Comprehensive Review.

J Pers Med. 2022-12-19

[4]
Tooth abnormalities associated with non-syndromic cleft lip and palate: systematic review and meta-analysis.

Clin Oral Investig. 2022-8

[5]
Detection and classification of unilateral cleft alveolus with and without cleft palate on panoramic radiographs using a deep learning system.

Sci Rep. 2021-8-6

[6]
Craniofacial malformations and their association with brain development: the importance of a multidisciplinary approach for treatment.

Odontology. 2019-6-6

本文引用的文献

[1]
Teeth agenesis evaluation in an Italian sample of complete unilateral and bilateral cleft lip and palate patients.

Minerva Stomatol. 2018-8

[2]
A cross-sectional analysis of the prevalence of tooth agenesis and structural dental anomalies in association with cleft type in non-syndromic oral cleft patients.

Prog Orthod. 2017-6-25

[3]
Canine Eruption After Secondary Alveolar Bone Graft in Unilateral Cleft Lip and Palate Patients.

J Craniofac Surg. 2017-7

[4]
Temporal trend in the reported birth prevalence of cleft lip and/or cleft palate in Brazil, 2000 to 2013.

Birth Defects Res A Clin Mol Teratol. 2016-9

[5]
Dental Anomalies in a Brazilian Cleft Population.

Cleft Palate Craniofac J. 2016-11

[6]
Spectrum of Dental Phenotypes in Nonsyndromic Orofacial Clefting.

J Dent Res. 2015-7

[7]
Dental anomalies in the incisor-canine region in patients with cleft lip and palate - literature review.

Dev Period Med. 2014

[8]
Associations between the risk of tooth agenesis and single-nucleotide polymorphisms of MSX1 and PAX9 genes in nonsyndromic cleft patients.

Angle Orthod. 2013-5-29

[9]
Is missing maxillary lateral incisor in complete cleft lip and palate a product of genetics or local environment?

Angle Orthod. 2012-5-17

[10]
Prevalence of Dental Anomalies in Patients With Nonsyndromic Cleft Lip and/or Palate in a Brazilian Population.

Cleft Palate Craniofac J. 2013-7

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