Paranaiba Lívia Máris Ribeiro, Coletta Ricardo D, Swerts Mário Sérgio Oliveira, Quintino Rafaela Pacífico, de Barros Letízia Monteiro, Martelli-Júnior Hercílio
Cleft Palate Craniofac J. 2013 Jul;50(4):400-5. doi: 10.1597/11-029. Epub 2011 Oct 5.
Objective : Many studies have demonstrated a high frequency of dental anomalies in patients with cleft lip and/or palate. Because dental anomalies may complicate dental treatment, we investigated the prevalence of dental anomalies in a group of Brazilian patients with nonsyndromic cleft lip and/or palate. Design, Participants, Setting : Retrospective analysis was performed using clinical records of 296 patients aged between 12 and 30 years with repaired nonsyndromic cleft lip and/or palate without history of tooth extraction and orthodontic treatment. Associations between oral clefts and presence of dental anomalies outside the cleft area were investigated. Results : Dental anomalies were identified in 39.9% of the nonsyndromic cleft lip and/or palate patients, and tooth agenesis (47.5%), impacted tooth (13.1%), and microdontia (12.7%) were the most common anomalies. Cleft lip patients were less affected by dental anomalies compared with cleft palate or cleft lip and palate patients (p = .057). Specifically, patients with unilateral cleft lip and palate were significantly more affected by dental anomalies than those with bilateral cleft lip and palate (p = .00002), and individuals with unilateral complete cleft lip and palate (p = .002) and complete cleft palate (p = .01) were significantly more affected by tooth agenesis than other cleft types. Agenesis of the premolars (p = .043) and maxillary lateral incisors (p = .03) were significantly more frequent in patients with unilateral complete cleft lip and palate. Conclusions : The present study revealed a high frequency of dental anomalies in nonsyndromic cleft lip and/or palate patients and further demonstrated that patients with unilateral cleft lip and palate were frequently more affected by dental anomalies than those with bilateral cleft lip and palate. Moreover, our results demonstrate that dental anomalies should be considered during dental treatment planning for individuals affected by nonsyndromic cleft lip and/or palate.
许多研究表明唇腭裂患者中牙齿异常的发生率很高。由于牙齿异常可能使牙科治疗复杂化，我们调查了一组巴西非综合征性唇腭裂患者的牙齿异常患病率。设计、参与者、背景：采用296例年龄在12至30岁之间、已修复非综合征性唇腭裂且无拔牙和正畸治疗史患者的临床记录进行回顾性分析。研究了口腔裂隙与裂隙区域外牙齿异常的相关性。结果：在非综合征性唇腭裂患者中，39.9%存在牙齿异常，其中最常见的异常为牙齿缺失（47.5%）、阻生牙（13.1%）和过小牙（12.7%）。与腭裂或唇腭裂患者相比，唇裂患者受牙齿异常的影响较小（p = 0.057）。具体而言，单侧唇腭裂患者比双侧唇腭裂患者受牙齿异常的影响显著更大（p = 0.00002），单侧完全性唇腭裂患者（p = 0.002）和完全性腭裂患者（p = 0.01）比其他腭裂类型患者受牙齿缺失的影响显著更大。单侧完全性唇腭裂患者中前磨牙缺失（p = 0.043）和上颌侧切牙缺失（p = 0.03）更为常见。结论：本研究揭示了非综合征性唇腭裂患者中牙齿异常的高发生率，并进一步表明单侧唇腭裂患者比双侧唇腭裂患者更常受牙齿异常影响。此外，我们的结果表明，在为非综合征性唇腭裂患者制定牙科治疗计划时应考虑牙齿异常情况。
