Srigley J R, Toth P, Edwards V
Clin Lab Med. 1987 Mar;7(1):91-115.
As illustrated in this review, neoplasms of the male genital tract are markedly heterogenous, reflecting their complex embryologic derivation and histogenetic classification. Transmission electron microscopy has greatly increased our understanding of the structure of these tumors, and in doing so has greatly improved our light microscopy. Additionally, in a number of selected situations, TEM also provides important practical diagnostic information. Currently, light microscopy in conjunction with clinical information is the central tool of tumor taxonomy. However, TEM with histochemistry, immunohistology, analytic cytometry, and molecular biology provide practical and useful information in some situations. In all cases, the application of these techniques has greatly increased our overall understanding of tumor structure, pathobiology, and classification.
正如本综述所示，男性生殖道肿瘤具有显著的异质性，这反映了它们复杂的胚胎学起源和组织发生学分类。透射电子显微镜极大地增进了我们对这些肿瘤结构的理解，并且在此过程中极大地改进了我们的光学显微镜检查。此外，在一些特定情况下，透射电子显微镜还提供重要的实际诊断信息。目前，结合临床信息的光学显微镜检查是肿瘤分类学的核心工具。然而，透射电子显微镜与组织化学、免疫组织学、分析细胞术和分子生物学在某些情况下提供了实用且有用的信息。在所有情况下，这些技术的应用极大地增进了我们对肿瘤结构、病理生物学和分类的整体理解。
