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既往牙外伤与牙外伤新病例的关系。一项系统评价与荟萃分析。

The relationship of previous dental trauma with new cases of dental trauma. A systematic review and meta-analysis.

作者信息

Magno Marcela B, Neves Aline B, Ferreira Daniele M, Pithon Matheus M, Maia Lucianne C

机构信息

Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Central Library of the Health Science Center, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

出版信息

Dent Traumatol. 2019 Feb;35(1):3-14. doi: 10.1111/edt.12449. Epub 2018 Nov 5.

Abstract

BACKGROUND/AIMS: Traumatic dental injuries (TDI) are a public health concern with high prevalence and recurrence rate. The aim of this study was to perform a systematic review and meta-analysis to determine whether previous dental trauma is a predictive factor for new episodes of TDI (recurrence or first episodes).

MATERIALS AND METHODS

Electronic searches were performed with no language or date restrictions. According to the PECOS strategy, cohort studies that investigated subjects with and without previous TDI, and its association with new TDI episodes, as primary or secondary outcomes, were included. Quality assessment and bias control were carried out according to Fowkes and Fulton guidelines. A meta-analysis was performed by sub-grouping studies into deciduous and permanent dentition, and the risk ratio (RR) was also calculated (P ≤ 0.05). The evidence was quality-tested using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

RESULTS

After titles and abstracts were examined, and full texts were read, five studies were included in this systematic review. Four studies had high methodological quality, and one presented a risk of bias on confounding factors. No association and a positive association were determined between previous history of TDI and new episodes of TDI in the primary (RR 1.26 [0.99, 1.62], P = 0.06) and in the permanent dentitions (RR 2.68 [1.20, 4.19], I  = 37%, P < 0.00001), respectively. The pooled results demonstrated a positive association (P < 0.00001) between previous dental trauma and new episodes of TDI (RR 2.17 [1.20, 3.90], P = 0.01, I  = 83%) with moderate evidence quality level.

CONCLUSIONS

Individuals that have suffered previous TDI present a greater risk of suffering new episodes of TDI.

摘要

背景/目的:创伤性牙损伤(TDI)是一个备受关注的公共卫生问题,其患病率和复发率都很高。本研究的目的是进行一项系统评价和荟萃分析,以确定既往牙外伤是否是TDI新发病例(复发或首次发作)的预测因素。

材料与方法

进行电子检索,无语言或日期限制。根据PECOS策略,纳入调查有或无既往TDI受试者及其与新TDI发作的关联作为主要或次要结局的队列研究。根据福克斯和富尔顿指南进行质量评估和偏倚控制。通过将研究分为乳牙列和恒牙列进行亚组荟萃分析,并计算风险比(RR)(P≤0.05)。使用推荐分级评估、制定和评价(GRADE)方法对证据进行质量检验。

结果

在检查标题和摘要并阅读全文后,本系统评价纳入了五项研究。四项研究具有较高的方法学质量,一项研究在混杂因素方面存在偏倚风险。在乳牙列中,既往TDI史与TDI新发病例之间未发现关联(RR 1.26 [0.99, 1.62],P = 0.06),而在恒牙列中发现正相关(RR 2.68 [1.20, 4.19],I = 37%,P < 0.00001)。汇总结果显示,既往牙外伤与TDI新发病例之间存在正相关(P < 0.00001)(RR 2.17 [1.20, 3.90],P = 0.01,I = 83%),证据质量水平为中等。

结论

既往患有TDI的个体发生TDI新发病例的风险更高。

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