Eastern Regional Research Center , Agricultural Research Service, U.S. Department of Agriculture, Wyndmoor, Pennsylvania.
Foodborne Pathog Dis. 2019 Feb;16(2):90-93. doi: 10.1089/fpd.2018.2513. Epub 2018 Oct 10.
There are reports in the literature stating that Campylobacter infections can cause hemolytic uremic syndrome (HUS); however, a mechanism for how Campylobacter induces HUS has not been proposed by investigators. The most common bacterial inducer of HUS is the Shiga toxin-producing Escherichia coli (STEC), and a few cases of HUS are induced by an invasive Shigella dysenteriae or Streptococcus pneumoniae infection. Campylobacter spp. have not been shown to produce Shiga toxin (Stx) nor do they possess genetic elements capable of producing a Stx-like toxin. The neuraminidase associated with pneumococcal HUS has not been observed in Campylobacter. Therefore, in the absence of a well-defined toxic mechanism, it not clear that Campylobacter actually causes HUS.
文献中有报道称弯曲杆菌感染可引起溶血性尿毒症综合征（HUS）；然而，研究人员尚未提出弯曲杆菌引起 HUS 的机制。引起 HUS 的最常见细菌诱导剂是产志贺毒素大肠杆菌（STEC），少数 HUS 是由侵袭性痢疾志贺菌或肺炎链球菌感染引起的。弯曲杆菌属未被证实能产生志贺毒素（Stx），也没有能够产生类志贺毒素的遗传元件。肺炎球菌 HUS 相关的神经氨酸酶在弯曲杆菌中未被观察到。因此，在没有明确的毒性机制的情况下，尚不清楚弯曲杆菌是否真的会引起 HUS。
