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轻度创伤性脑损伤后重返工作岗位的系统评价与荟萃分析

A systematic review and meta-analysis of return to work after mild Traumatic brain injury.

作者信息

Bloom Ben, Thomas Stephen, Ahrensberg Jette Møller, Weaver Rachel, Fowler Alex, Bestwick Jon, Harris Tim, Pearse Rupert

机构信息

a William Harvey Institute , Queen Mary University of London , London , UK.

b Emergency Department , Royal London Hospital, Barts Health NHS Trust , London , UK.

出版信息

Brain Inj. 2018;32(13-14):1623-1636. doi: 10.1080/02699052.2018.1532111. Epub 2018 Oct 11.

Abstract

OBJECTIVE

To perform a systematic review and meta-analysis of return to work (RTW) times for adult patients with mild traumatic brain injury (mTBI).

METHODS

Six databases and six trials registries were searched. Inclusion: studies reporting RTW, > 30 patients, adults, with mTBI. Exclusion: final measurement RTW < 30 days after injury, first measurement > 1 year.

RESULTS

Of 978 records, 14 eligible studies were identified. Two included patients exclusively in paid employment pre-injury; four included paid employment, students, homemakers or other activities; seven included pre-injury occupational status described but unclear; one included patients whose pre-injury occupational status not described. Three reported average RTW, 12 reported proportions of patients RTW at pre-specified time-points (1 both). Average RTW times varied from 13 to 93 days. At 1 month the proportion of patients RTW (three pooled studies) was 0.56 (95% CI 0.30-0.79), at 6 months (six studies) 0.83 (0.74-0.89), at 12 months (seven studies) 0.89 (0.83-0.93).

CONCLUSION

More than half of patients with mTBI have returned to work by 1 month after injury, and more than 80% by 6 months. Most studies had poor internal validity. Reporting of outcomes in mTBI is variable, and this accounted for some of the heterogeneity found in this review.

摘要

目的

对成年轻度创伤性脑损伤(mTBI)患者的重返工作岗位(RTW)时间进行系统评价和荟萃分析。

方法

检索了六个数据库和六个试验注册库。纳入标准:报告RTW的研究,患者超过30例,成年mTBI患者。排除标准:伤后最终测量RTW<30天,首次测量>1年。

结果

在978条记录中,确定了14项符合条件的研究。两项研究仅纳入伤前有带薪工作的患者;四项研究纳入了带薪工作、学生、家庭主妇或其他活动的患者;七项研究描述了伤前职业状况但不明确;一项研究纳入了伤前职业状况未描述的患者。三项研究报告了平均RTW时间,12项研究报告了在预先设定时间点RTW的患者比例(其中一项同时报告了两者)。平均RTW时间从13天到93天不等。在1个月时,RTW的患者比例(三项汇总研究)为0.56(95%CI 0.30-0.79),在6个月时(六项研究)为0.83(0.74-0.89),在12个月时(七项研究)为0.89(0.83-0.93)。

结论

超过一半的mTBI患者在伤后1个月内重返工作岗位,6个月时超过八成。大多数研究的内部效度较差。mTBI结局报告存在差异,这是本评价中发现的部分异质性原因。

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