Lakicevic Nemanja, Andjelic Bogdan, Manojlovic Marko, Gentile Ambra, Bianco Antonino, Paoli Antonio, Leonov Sergey, Pashchenko Alexander, Drid Patrik
Faculty of Psychology, Lomonosov Moscow State University, Moscow, Russia; 2Federal Scientific Center of Psychological and Interdisciplinary Research, MoscowFaculty of Psychology, Lomonosov Moscow State University, Moscow, Russia; Federal Scientific Center of Psychological and Interdisciplinary Research, Moscow.
Sport and Exercise Sciences Research Unit, University of Palermo, Palermo.
Eur J Transl Myol. 2025 Jun 27;35(2). doi: 10.4081/ejtm.2025.13275. Epub 2025 Apr 10.
Traumatic Brain Injury (TBI) is the leading cause of injury-related death worldwide. In recent years, Virtual Reality (VR) has emerged as a promising diagnostic and treatment tool capable of improving Cognitive Function (CF) after TBI. We sought to review the literature on this issue systematically. Web of Science, PubMed and PsycINFO were screened for relevant literature. Only randomized control trials whereby TBI-affected individuals underwent VR training and control groups received standard rehabilitative care were included. Screening, quality appraisal and data extraction were conducted by independent reviewers using a standardized protocol. Six studies of ~300 participants met the inclusion criteria and showed that both groups improved their overall CF post-intervention. However, non-immersive and semi-immersive VR groups had markedly better scores in all of the cognitive domains measured when compared to non-VR groups. VR is a potent post-TBI rehabilitative tool that can improve CF in this population and facilitate the return-to-work process. Future studies should adopt a similar design yet use fully immersive VR to enhance CF potentially to a greater degree.
创伤性脑损伤（TBI）是全球与损伤相关死亡的主要原因。近年来，虚拟现实（VR）已成为一种有前景的诊断和治疗工具，能够改善创伤性脑损伤后的认知功能（CF）。我们试图系统地回顾关于这个问题的文献。对科学网、PubMed和PsycINFO进行筛选以查找相关文献。仅纳入了受创伤性脑损伤影响的个体接受虚拟现实训练且对照组接受标准康复护理的随机对照试验。由独立评审人员使用标准化方案进行筛选、质量评估和数据提取。六项涉及约300名参与者的研究符合纳入标准，结果显示两组在干预后整体认知功能均有所改善。然而，与非虚拟现实组相比，非沉浸式和半沉浸式虚拟现实组在所有测量的认知领域得分均明显更高。虚拟现实是一种有效的创伤性脑损伤后康复工具，可改善该人群的认知功能并促进重返工作岗位的进程。未来的研究应采用类似的设计，但使用完全沉浸式虚拟现实，以更大程度地潜在改善认知功能。
