Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland.
National Centre for Sports Medicine, Warsaw, Poland.
PLoS One. 2018 Oct 11;13(10):e0205459. doi: 10.1371/journal.pone.0205459. eCollection 2018.
Application of normative data for echocardiographic measurements to children practicing sports may lead to false positive findings. The aim of the study was to define the normative data of basic echocardiographic measurements for this group and to compare them to the previously published normative data for the pediatric population.
Parasternal long-axis 2D-guided echocardiographic measurements were obtained from a group of 791 child athletes (ages 5-18 years). According to the methodology presented previously by Pettersen et al. (2008), the regression equations for basic cardiac dimensions against body surface area were derived and individual Z-scores values were computed, using both Pettersen's equations and newly derived ones.
Z-scores computed based on Pettersen's equations were found to differ significantly from those based on the new equations, for all the analyzed parameters (p<0.001). In agreement analysis, the most pronounced differences were found for the left atrium, interventricular septum and the left ventricular posterior wall. However, in most cases, the indications of abnormality were concordant (91.8%-97.6%); except for the left atrium, where there were 30.8% discordant results.
The study presents normative data for basic echocardiographic cardiac measurements for children of both sexes practicing varying sporting disciplines and compares them with general pediatric population. Mean values of cardiac dimensions are higher in young athletes, particularly in relation to the left atrium and left ventricular muscle thickness. In most cases, the upper limit of normality observed in the young athletes is confined within the upper limit of the general pediatric population.
将超声心动图测量的参考值应用于进行体育运动的儿童可能会导致假阳性结果。本研究的目的是为该人群定义基本超声心动图测量的参考值,并将其与之前发表的儿科人群参考值进行比较。
从一组 791 名儿童运动员(年龄 5-18 岁)中获得胸骨旁长轴二维引导的超声心动图测量值。根据 Pettersen 等人(2008 年)提出的方法,得出了基本心脏尺寸与体表面积的回归方程,并使用 Pettersen 方程和新推导的方程计算了个体 Z 分数值。
基于 Pettersen 方程计算的 Z 分数与基于新方程计算的 Z 分数存在显著差异,所有分析参数均如此(p<0.001)。在一致性分析中,左心房、室间隔和左心室后壁的差异最为明显。然而,在大多数情况下,异常的指示是一致的(91.8%-97.6%);除了左心房,其中有 30.8%的结果不一致。
本研究为从事不同运动项目的男女儿童的基本超声心动图心脏测量提供了参考值,并将其与一般儿科人群进行了比较。年轻运动员的心脏尺寸平均值较高,尤其是左心房和左心室肌肉厚度。在大多数情况下,在年轻运动员中观察到的正常值上限局限于一般儿科人群的正常值上限内。