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蕈样肉芽肿肿瘤细胞的免疫细胞特征分析

Immunocytological characterization of the mycosis fungoides tumour cell.

作者信息

Claudy A L, Schmitt D, Alario A, Brochier J, Perrot H, Thivolet J

出版信息

Bull Cancer. 1977;64(2):241-8.

PMID:303133
Abstract

The immunocytological identification of the mycosis fungoides cell was carried out on cells extracted from the tumorous nodules of a patient suffering from typical mycosis fungoides. Various techniques, such as E and IgM-EAC rosettes and examination for surface membrane immunoglobulins, were performed on the peripheral blood cells and the tumour cell. Membrane staining with a specific anti-T lymphocyte serum conjugated with peroxidase confirmed the thymodependent origin of the mycosis fungoides cell. However, the immunolabelling (with Fab peroxidase conjugate was found constantly negative.

摘要

对一名典型蕈样肉芽肿患者肿瘤结节中提取的细胞进行了蕈样肉芽肿细胞的免疫细胞学鉴定。对外周血细胞和肿瘤细胞进行了多种技术检测,如E和IgM-EAC花环试验以及表面膜免疫球蛋白检测。用与过氧化物酶偶联的特异性抗T淋巴细胞血清进行膜染色,证实了蕈样肉芽肿细胞起源于胸腺依赖细胞。然而,发现用Fab过氧化物酶偶联物进行的免疫标记始终为阴性。

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