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乳腺摄影、数字乳腺断层合成和专用乳腺 CT 的腺体剂量标准化系数。

Normalized glandular dose coefficients in mammography, digital breast tomosynthesis and dedicated breast CT.

机构信息

Dipartimento di Fisica "Ettore Pancini", Università di Napoli Federico II, Napoli, Italy; INFN Sezione di Napoli, Napoli, Italy.

Dipartimento di Fisica "Ettore Pancini", Università di Napoli Federico II, Napoli, Italy; INFN Sezione di Napoli, Napoli, Italy.

出版信息

Phys Med. 2018 Nov;55:142-148. doi: 10.1016/j.ejmp.2018.09.002. Epub 2018 Oct 9.

DOI:10.1016/j.ejmp.2018.09.002
PMID:30314732
Abstract

PURPOSE

To provide mean glandular dose (MGD) estimates via Monte Carlo (MC) simulations as a function of the breast models and scan parameters in mammography, digital breast tomosynthesis (DBT) and dedicated breast CT (BCT).

METHODS

The MC code was based on GEANT4 toolkit. The simulated compressed breast was either a cylinder with a semi-circular section or ad hoc shaped for oblique view (MLO). In DBT we studied the influence of breast models and exam parameters on the T-factors (i.e. the conversion factor for the calculation of the MGD in DBT from that for a 0-degree projection), and in BCT we investigated the influence on the MGD estimates of the ion chamber volume used for the air kerma measurements.

RESULTS

In mammography, a model representative of a breast undergoing an MLO view exam did not produce substantial differences (0.4%) in MGD estimates, when compared to a conventional cranio-caudal (CC) view breast model. The beam half value layer did not present a significant influence on T-factors in DBT (<0.8%), while the skin model presented significant influence on MGD estimates (up to 3.3% at 30 degrees scan angle), increasing for larger scan angles. We derived a correction factor for taking into account the different ion chamber volume used in MGD estimates in BCT.

CONCLUSIONS

A series of MC code modules for MGD estimates in 2D and 3D breast imaging have been developed in order to take into account the most recent advances in breast models.

摘要

目的

通过蒙特卡罗(MC)模拟,提供乳房模型和乳腺摄影、数字乳腺断层合成(DBT)和专用乳腺 CT(BCT)扫描参数的平均腺体剂量(MGD)估计值。

方法

MC 代码基于 GEANT4 工具包。模拟的压缩乳房为具有半圆形截面的圆柱体或用于斜视图(MLO)的特定形状。在 DBT 中,我们研究了乳房模型和检查参数对 T 因子(即从 0 度投影计算 DBT 中 MGD 的转换因子)的影响,在 BCT 中,我们研究了用于空气比释动能测量的离子室体积对 MGD 估计值的影响。

结果

在乳腺摄影中,与传统的颅尾(CC)视图乳房模型相比,代表进行 MLO 视图检查的乳房的模型在 MGD 估计值方面没有产生实质性差异(0.4%)。在 DBT 中,束半值层对 T 因子没有显著影响(<0.8%),而皮肤模型对 MGD 估计值有显著影响(在 30 度扫描角度下高达 3.3%),随着扫描角度的增大而增大。我们推导出了一个校正因子,用于考虑 BCT 中用于 MGD 估计的不同离子室体积。

结论

为了考虑乳房模型的最新进展,我们开发了一系列用于 2D 和 3D 乳房成像的 MGD 估计 MC 代码模块。

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