寡排卵在有记录的子宫内膜异位症患者中并非罕见特征。
Oligo-anovulation is not a rarer feature in women with documented endometriosis.
机构信息
Department of Gynaecology Obstetrics II and Reproductive Medicine, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Universitaire Paris Centre, Centre Hospitalier Universitaire (CHU) Cochin, Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Department of Development, Reproduction and Cancer, Institut Cochin, INSERM U1016, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Department of Gynaecology Obstetrics II and Reproductive Medicine, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Universitaire Paris Centre, Centre Hospitalier Universitaire (CHU) Cochin, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
出版信息
Fertil Steril. 2018 Oct;110(5):941-948. doi: 10.1016/j.fertnstert.2018.06.012.
OBJECTIVE
To study the prevalence of oligo-anovulation in women suffering from endometriosis compared to that of women without endometriosis.
DESIGN
A single-center, cross-sectional study.
SETTING
University hospital-based research center.
PATIENT (S): We included 354 women with histologically proven endometriosis and 474 women in whom endometriosis was surgically ruled out between 2004 and 2016.
INTERVENTION
None.
MAIN OUTCOME MEASURE(S): Frequency of oligo-anovulation in women with endometriosis as compared to that prevailing in the disease-free reference group.
RESULTS
There was no difference in the rate of oligo-anovulation between women with endometriosis (15.0%) and the reference group (11.2%). Regarding the endometriosis phenotype, oligo-anovulation was reported in 12 (18.2%) superficial peritoneal endometriosis, 12 (10.6%) ovarian endometrioma, and 29 (16.6%) deep infiltrating endometriosis.
CONCLUSION(S): Endometriosis should not be discounted in women presenting with oligo-anovulation.
目的
研究与无子宫内膜异位症女性相比，患有子宫内膜异位症的女性中寡排卵的发生率。
设计
单中心、横断面研究。
地点
以大学医院为基础的研究中心。
患者
我们纳入了 2004 年至 2016 年间经组织学证实患有子宫内膜异位症的 354 名女性和手术排除子宫内膜异位症的 474 名女性。
干预措施
无。
主要观察指标
患有子宫内膜异位症的女性中寡排卵的频率与无疾病参考组中寡排卵的流行率比较。
结果
患有子宫内膜异位症的女性（15.0%）和参考组（11.2%）的寡排卵发生率无差异。关于子宫内膜异位症表型，12 例（18.2%）浅腹膜子宫内膜异位症、12 例（10.6%）卵巢子宫内膜异位囊肿和 29 例（16.6%）深部浸润性子宫内膜异位症存在寡排卵。
结论
患有子宫内膜异位症的女性出现寡排卵时不应忽视子宫内膜异位症的可能。
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