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Antimicrob Agents Chemother. 2023 Jul 18;67(7):e0025123. doi: 10.1128/aac.00251-23. Epub 2023 Jun 26.
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Potential anti-TB investigational compounds and drugs with repurposing potential in TB therapy: a conspectus.具有抗结核作用的潜在研究化合物和具有重新定位潜力的抗结核治疗药物：概述。
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本文引用的文献

1
MTBseq: a comprehensive pipeline for whole genome sequence analysis of complex isolates.MTBseq：用于复杂分离株全基因组序列分析的综合流程
PeerJ. 2018 Nov 13;6:e5895. doi: 10.7717/peerj.5895. eCollection 2018.
2
Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.鉴定噻吩型吗啉寡聚体作为新型结核分枝杆菌抑制剂，针对 QcrB。
J Med Chem. 2018 Aug 9;61(15):6592-6608. doi: 10.1021/acs.jmedchem.8b00172. Epub 2018 Jul 26.
3
Ecology and evolution of Mycobacterium tuberculosis.结核分枝杆菌的生态学与进化。
Nat Rev Microbiol. 2018 Apr;16(4):202-213. doi: 10.1038/nrmicro.2018.8. Epub 2018 Feb 19.
4
Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort.兰索拉唑的使用与英国临床实践研究数据链中的结核病发病率：一项基于人群的队列研究。
PLoS Med. 2017 Nov 21;14(11):e1002457. doi: 10.1371/journal.pmed.1002457. eCollection 2017 Nov.
5
Improved Phenoxyalkylbenzimidazoles with Activity against Mycobacterium tuberculosis Appear to Target QcrB.对结核分枝杆菌具有活性的改良苯氧基烷基苯并咪唑似乎靶向QcrB。
ACS Infect Dis. 2017 Dec 8;3(12):898-916. doi: 10.1021/acsinfecdis.7b00112. Epub 2017 Oct 31.
6
Activity of 2-(quinolin-4-yloxy)acetamides in Mycobacterium tuberculosis clinical isolates and identification of their molecular target by whole-genome sequencing.2-(喹啉-4-基氧基)乙酰胺类化合物在结核分枝杆菌临床分离株中的活性及全基因组测序鉴定其分子靶标。
Int J Antimicrob Agents. 2018 Mar;51(3):378-384. doi: 10.1016/j.ijantimicag.2017.08.023. Epub 2017 Aug 23.
7
Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent.兰索拉唑硫化物，这种有前景的抗结核药物的药代动力学。
Biomed Chromatogr. 2017 Dec;31(12). doi: 10.1002/bmc.4035. Epub 2017 Jul 13.
8
SAR and identification of 2-(quinolin-4-yloxy)acetamides as cytochrome inhibitors.2-(喹啉-4-基氧基)乙酰胺作为细胞色素抑制剂的构效关系及鉴定
Medchemcomm. 2016 Nov 1;7(11):2122-2127. doi: 10.1039/c6md00236f. Epub 2016 Aug 22.
9
Twenty Years of Global Surveillance of Antituberculosis-Drug Resistance.全球抗结核药物耐药性监测二十年。
N Engl J Med. 2016 Sep 15;375(11):1081-9. doi: 10.1056/NEJMsr1512438.
10
Lansoprazole is an antituberculous prodrug targeting cytochrome bc1.兰索拉唑是一种靶向细胞色素bc1的抗结核前体药物。
Nat Commun. 2015 Jul 9;6:7659. doi: 10.1038/ncomms8659.

No Evidence for Acquired Mutations Associated with Cytochrome Inhibitor Resistance in 13,559 Clinical Mycobacterium tuberculosis Complex Isolates.

作者信息

Rybniker Jan, Kohl Thomas Andreas, Barilar Ivan, Niemann Stefan

机构信息

Department of Internal Medicine, University Hospital of Cologne, Cologne, Germany

German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.

出版信息

Antimicrob Agents Chemother. 2018 Dec 21;63(1). doi: 10.1128/AAC.01317-18. Print 2019 Jan.

DOI:10.1128/AAC.01317-18
PMID:30323041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6325196/
Abstract
摘要