Patidar Deepika, Sogi Suma, Singh Varsha, Shinu P, Loomba Ashish, Patidar Dinesh Chand
Department of Pediatric and Preventive Dentistry, Maharishi Markandeshwar College of Dental Sciences and Research, Ambala, Haryana, India.
Department of Microbiology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, Haryana, India.
J Indian Soc Pedod Prev Dent. 2018 Oct-Dec;36(4):386-390. doi: 10.4103/JISPPD.JISPPD_204_18.
The oral microflora primarily involved in early childhood caries (ECC) is Streptococcus mutans while Streptococcus sanguinis is related to healthy caries-free mouth. The antagonism between the two at biological level is well recognized.
This study aims to compare the pre- and posttreatment salivary levels of S. mutans and S. sanguinis in ECC.
This cross-sectional study was performed on 40 eligible participants. Clinical examination was done, and decayed teeth were recorded. Pre- and Posttreatment saliva sample was taken, processed and bacterial counts were compared.
A statistically significant posttreatment reduction was found in S. mutans counts; however, a significant posttreatment elevation was seen in S. sanguinis counts (P < 0.001) using Wilcoxon signed-rank test. A significant weak positive correlation was found between S. mutans and decayed teeth in the mouth (r = 0.366 and P = 0.028) using Spearman's correlation. No significant gender association was found between pre- and posttreatment S. mutans and S. sanguinis counts (P = 0.908) and also between decayed teeth (P = 0.321) using Mann-Whitney U-test.
Complete dental treatment procedure showed significant reduction and elevation in S. mutans and S. sanguinis counts, respectively. A positive association was observed between S. mutans and ECC while S. sanguinis were positively associated with posttreatment oral environment.
主要参与幼儿龋齿（ECC）的口腔微生物群是变形链球菌，而血链球菌与无龋健康口腔有关。两者在生物学水平上的拮抗作用已得到充分认识。
本研究旨在比较ECC患者治疗前后变形链球菌和血链球菌的唾液水平。
对40名符合条件的参与者进行了这项横断面研究。进行了临床检查，并记录了龋齿情况。采集治疗前和治疗后的唾液样本，进行处理并比较细菌计数。
使用Wilcoxon符号秩检验发现，治疗后变形链球菌计数有统计学意义的降低；然而，治疗后血链球菌计数有显著升高（P < 0.001）。使用Spearman相关性分析发现，口腔中变形链球菌与龋齿之间存在显著的弱正相关（r = 0.366，P = 0.028）。使用Mann-Whitney U检验发现，治疗前后变形链球菌和血链球菌计数之间以及龋齿之间均未发现显著的性别关联（P = 0.908和P = 0.321）。
完整的牙科治疗程序分别显示变形链球菌和血链球菌计数显著降低和升高。观察到变形链球菌与ECC呈正相关，而血链球菌与治疗后的口腔环境呈正相关。
