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基于模板的“穿刺与打印”技术用于获取成形角膜移植片以治疗周边角膜穿孔

Stenciling-Based "Prick and Print" Technique for Harvesting Shaped Corneal Grafts for Management of Peripheral Corneal Perforations.

作者信息

Parmar Gautam Singh, Ghodke Bhushan, Bose Sunandini, Meena Ashok Kumar

机构信息

Department of Cornea and Refractive Services, Sadguru Seva Sang Trust, Chitrakoot, Madhya Pradesh, India.

出版信息

Cornea. 2019 Jan;38(1):105-109. doi: 10.1097/ICO.0000000000001774.

Abstract

PURPOSE

To evaluate a new surgical technique ("prick and print") for harvesting shaped donor corneal grafts in cases with perforated peripheral ulcerative keratitis (PUK).

METHODS

We conducted a retrospective case series at a tertiary center. Medical records of 13 patients with perforated PUK, who underwent tectonic eccentric keratoplasty using the stenciling-based prick and print technique during the past 1 year, were reviewed. All patients (15 eyes of 13 patients) received grafts of varying sizes and shapes (14 crescentic and 1 biconvex). Factors evaluated were tectonic integrity, graft apposition, and complications, if any. Surgical success was defined as maintenance of corneal integrity and healing of PUK.

RESULTS

Mean age of patients was 40.6 ± 19.4 years. Mean follow-up was 10 months. We achieved surgical success in 80% (12/15 eyes) of cases. Two eyes had graft infection, and regrafting (large circular graft) was performed for both. One eye developed new-site PUK, which was managed medically, and the graft remained viable tectonically. After surgery, 9 eyes achieved a best-corrected visual acuity of logarithm of the minimum angle of resolution +0.3 or better. No cases had graft rejection or peripheral anterior synechiae by final follow-up.

CONCLUSIONS

The stenciling-based prick and print technique for making shaped donor corneal grafts may offer a simple, easy-to-learn surgical technique that can be used to make any shape or pattern of donor corneal grafts without involving the optical center, even in extensive peripheral corneal lesions.

摘要

目的

评估一种用于在穿孔性周边溃疡性角膜炎(PUK)病例中获取成形供体角膜移植物的新手术技术(“穿刺与印记”)。

方法

我们在一家三级中心进行了一项回顾性病例系列研究。回顾了过去1年中13例接受基于模板的穿刺与印记技术进行的构造性偏心角膜移植术的穿孔性PUK患者的病历。所有患者(13例患者的15只眼)均接受了不同大小和形状的移植物(14个新月形和1个双凸形)。评估的因素包括构造完整性、移植物贴合情况以及并发症(如有)。手术成功定义为角膜完整性的维持和PUK的愈合。

结果

患者的平均年龄为40.6±19.4岁。平均随访时间为10个月。我们在80%(12/15只眼)的病例中取得了手术成功。2只眼发生了移植物感染,均进行了再次移植(大圆形移植物)。1只眼出现了新部位的PUK,经药物治疗,移植物在构造上仍保持存活。术后,9只眼的最佳矫正视力达到最小分辨角对数+0.3或更好。最终随访时,没有病例发生移植物排斥或周边前粘连。

结论

基于模板的穿刺与印记技术制作成形供体角膜移植物可能提供一种简单、易于学习的手术技术,可用于制作任何形状或图案的供体角膜移植物,而不涉及光学中心,即使在广泛的周边角膜病变中也是如此。

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