一项为期 12 个月的生活方式干预计划可改善肥胖患者的身体成分并降低糖尿病前期的患病率。
A 12-Month Lifestyle Intervention Program Improves Body Composition and Reduces the Prevalence of Prediabetes in Obese Patients.
出版信息
Obes Facts. 2018;11(5):393-399. doi: 10.1159/000492604. Epub 2018 Oct 17.
Abstract
BACKGROUND
The present study investigated the effects of a 12-month interdisciplinary standardized lifestyle program addressing physical activity and changes in dietary and lifestyle behavior in 2,227 obese prediabetic participants.
METHODS
Measures of obesity (BMI, waist circumference), cardiopulmonary fitness, and metabolic parameters were determined before and after the intervention period.
RESULTS
From the 2,227 participants who were initially prediabetic, 839 participants (-37.7%) did no longer show the criteria of prediabetes after the intervention and had normal HbA1c levels.
CONCLUSION
The clinical effects are substantial, and it is likely that the applied intense and multidisciplinary lifestyle interventions could reduce the risk of developing diabetes and the prevalence of a full-blown metabolic syndrome in obese and prediabetic patients.
摘要
背景
本研究调查了一项为期 12 个月的跨学科标准化生活方式计划对 2227 名肥胖前驱糖尿病患者的身体活动以及饮食和生活方式行为改变的影响。
方法
在干预前后测定肥胖（BMI、腰围）、心肺功能和代谢参数。
结果
在最初患有前驱糖尿病的 2227 名参与者中，839 名（-37.7%）在干预后不再符合前驱糖尿病的标准，且糖化血红蛋白水平正常。
结论
临床效果显著，应用强化多学科生活方式干预可能降低肥胖和前驱糖尿病患者发生糖尿病和完全代谢综合征的风险。
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