Department of Human Nutrition, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.
Nutrients. 2018 Oct 15;10(10):1504. doi: 10.3390/nu10101504.
The effect that blood glucose concentration has on feelings of satiety is unclear. Our aims were to assess satiety and subsequent energy intake following the ingestion of trifle sweetened with sucrose or isomaltulose whilst measuring plasma glucose concentration to confirm glycemic differences between trifles. Seventy-seven healthy adults participated in a double-blind crossover trial where trifle sweetened with sucrose or isomaltulose was consumed on separate days with a two-week washout. Blood was sampled at the baseline, 1 and 2 h postprandially, and satiety assessed using visual analogue scales (VAS). Weighed diet records were taken on test days. A statistically significant difference in blood glucose concentration between trifles was found at 60 min following consumption, with the isomaltulose trifle having a 0.69 mmol/L (95% confidence interval: -1.07, -0.31) lower concentration when compared with the sucrose trifle. Mean satiety response by area-under-the-curve (AUC) was not significantly different between trifles. Mean (SD) appetite scores for the sucrose and isomaltulose trifles were 4493 (2393) and 4527 (2590) mm·min, respectively, with a between trifle difference of -9 (95% CI: -589, 572) mm·min. Mean (SD) energy intake for the remainder of the day following trifle consumption was 3894 kJ (1950 kJ) and 3530 kJ (1926 kJ) after the sucrose and isomaltulose trifles, respectively, and was not significantly different ( = 0.133). The differing glycemic response to trifle was not related to satiety or to subsequent energy intake.
血糖浓度对饱腹感的影响尚不清楚。我们的目的是评估摄入添加蔗糖或异麦芽酮糖的乳蛋糕后饱腹感和随后的能量摄入情况，并测量血浆葡萄糖浓度以确认乳蛋糕之间的血糖差异。77 名健康成年人参加了一项双盲交叉试验，在该试验中，他们分别在两天内食用添加蔗糖或异麦芽酮糖的乳蛋糕，间隔两周洗脱期。在基线、餐后 1 小时和 2 小时采集血液样本，并使用视觉模拟量表（VAS）评估饱腹感。在测试日记录饮食量。在食用后 60 分钟时发现乳蛋糕之间的血糖浓度存在统计学显著差异，与蔗糖乳蛋糕相比，异麦芽酮糖乳蛋糕的浓度低 0.69mmol/L（95%置信区间：-1.07，-0.31）。通过曲线下面积（AUC）评估的平均饱腹感反应在乳蛋糕之间没有显著差异。蔗糖和异麦芽酮糖乳蛋糕的食欲评分平均值（SD）分别为 4493（2393）和 4527（2590）mm·min，乳蛋糕之间的差异为-9（95%CI：-589，572）mm·min。食用乳蛋糕后，其余时间的平均（SD）能量摄入分别为 3894kJ（1950kJ）和 3530kJ（1926kJ），在蔗糖和异麦芽酮糖乳蛋糕之间无显著差异（ = 0.133）。乳蛋糕血糖反应的差异与饱腹感或随后的能量摄入无关。
