对金属植入物的超敏反应：病理生理及诊断考量
Hypersensitivity to metallic implants: pathophysiologic and diagnostic considerations.
作者信息
Kounis Nicholas G, Koniari Ioanna
机构信息
University of Patras Medical School.
出版信息
Acta Biomed. 2018 Oct 8;89(3):428-429. doi: 10.23750/abm.v89i3.6718.
Metals are ubiquitous in the surrounding environment and constitute an important class of substances that can act as allergens. Consumer products such as earings, zip, jewellery, cosmetics, paints, dental and body implants as well as endovascular, intracardiac and orthopedic devices are made from metals. Metal anions eluted from various metals are common allergic sensitizers. In Europe nickel, chromium and cobalt induce allergic skin reactions in about 20%, 4%, and 7% while in the United States14%, 4%, and 9% respectively.
金属在周围环境中无处不在，是一类重要的可作为过敏原的物质。耳环、拉链、珠宝、化妆品、涂料、牙科和身体植入物以及血管内、心脏内和矫形器械等消费品都是由金属制成的。从各种金属中洗脱出来的金属阴离子是常见的过敏致敏剂。在欧洲，镍、铬和钴分别导致约20%、4%和7%的人出现过敏性皮肤反应，而在美国，这一比例分别为14%、4%和9%。
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