Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Department of Stomatology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
PLoS One. 2018 Oct 18;13(10):e0204797. doi: 10.1371/journal.pone.0204797. eCollection 2018.
To assess the quality and diagnostic accuracy of monochromatic images combined with adaptive statistical iterative reconstruction (ASIR) performed via spectral computed tomography (CT) in patients with Budd-Chiari syndrome (BCS).
Sixty-two patients with BCS underwent pectral CT with upper abdominal two-phase contrast-enhanced scanning to generate a 60keV monochromatic energy level combined with ASIR (ranging from 0% -100%) during the portal venous phase (PVP) and the hepatic venous phase (HVP). One-way ANOVA was used to compare vessel-to-liver contrast-to-noise ratio (CNR) for the portal vein (PV), hepatic vein (HV), and inferior vena cava (IVC). Subjective evaluations of the images in the three groups were conducted by image quality assessors and compared via Kruskal-Wallis H test.
The CNR values of the PV trunk, HV, IVC, liver parenchyma and pancreas were within ASIR (ranging from 0% - 100%) weight, and the difference were statistically significant (p <0.05). The highest overall image score was distributed at 50% ASIR weight value. Higher CNR values of HV, hepatic parenchyma and pancreas were obtained in the IVC type than in mixed and HV types (respective p values = 0.035, 0.019 and 0.042). Higher CNR values of the IVC were obtained in the HV type than in mixed and IVC types (p = 0.032). The CNR value of the IVC in the mixed type was less than that of the HV type (p = 0.028). The CNR values of the HV and liver parenchyma in mixed type were lower than those of the IVC type (p = 0.016 and 0.038, respectively). The CNR value of pancreas in IVC type was higher than that of the HV type (p = 0.037). The diagnostic value of CNR in patients with the IVC type was higher than that in patients with mixed and HV type, while the diagnostic value of CNR was found to be the lowest for the HV type (p = 0.043).
A monochromatic energy level of 60 keV with 50% ASIR can significantly improve image quality in cases of BCS.
评估能谱 CT 单能量成像结合自适应统计迭代重建(ASIR)在布加综合征(BCS)患者中的应用价值及图像质量。
对 62 例 BCS 患者进行上腹部双期增强扫描,在门静脉期(PVP)和肝静脉期(HVP)行 60keV 单能量成像,ASIR (0%-100%),对比门静脉(PV)、肝静脉(HV)、下腔静脉(IVC)的血管与肝脏噪声比(CNR)。采用单因素方差分析比较不同 ASIR 水平下的血管 CNR 值,观察者采用 5 分法对图像质量进行主观评分,采用 Kruskal-Wallis H 检验比较图像质量评分。
在不同 ASIR (0%-100%)水平下,PV 主干、HV、IVC、肝脏及胰腺的 CNR 值差异有统计学意义(p<0.05),当 ASIR 为 50%时,图像质量综合评分最高。HV 型 IVC 型的 HV、肝脏及胰腺 CNR 值均高于混合型及 HV 型(p 值分别为 0.035、0.019 和 0.042),HV 型 IVC 的 CNR 值高于混合型及 IVC 型(p=0.032),混合型 IVC 的 CNR 值低于 HV 型(p=0.028),HV 型及混合型的 HV、肝脏 CNR 值均低于 IVC 型(p 值分别为 0.016 和 0.038),IVC 型胰腺 CNR 值高于 HV 型(p=0.037)。IVC 型 CNR 值诊断效能最高,混合型及 HV 型依次降低(p=0.043)。
60keV 单能量结合 50%ASIR 可显著提高 BCS 患者的图像质量。