Department of Pulmonology, Intensive Care Medicine, Paracelsus Medical University, Nuremberg, Germany.
2nd Department of Medicine, Cardiovascular Medicine, Charles University in Prague U Nemocnice 2, Praha 2, 128 00, Czech Republic.
Resuscitation. 2018 Dec;133:108-117. doi: 10.1016/j.resuscitation.2018.10.014. Epub 2018 Oct 15.
Extracorporeal life support (ECLS) describes the use of blood perfusion devices to provide advanced cardiac or respiratory support. Advances in percutaneous vascular cannula insertion, centrifugal pump technologies, and the miniaturization of extracorporeal devices have simplified ECLS. The intention of this discussion is to review the role of ECLS as a potential rescue method for emergency department (ED) clinicians in critical clinical scenarios and to focus on the prerequisites for managing an ECLS program in an ED setting.
Possible indications for ECLS cannulation in the ED include ongoing circulatory arrest, shock or refractory hypoxemia and pulmonary embolism with refractory shock. Severe trauma, foreign body obstruction, hypothermia and near drowning are situations in which patients may potentially benefit from ECLS. Early stabilization in the ED can provide a time window for a diagnostic workup and/or urgent procedures, including percutaneous coronary intervention, rewarming or damage control surgery in trauma. The use of ECLS is resource intensive and can be associated with a high risk of complications, especially when performed without previous training. Therefore, ECLS should only be used when the underlying problem is potentially reversible, and the resources are available to address the etiology of organ dysfunction.
Emergent ECLS has a role in the ED for selected indications in the face of life-threatening conditions. ECLS provides a bridge to recovery, definitive therapy, intervention or surgery. ECLS program requires an appropriately trained staff (physicians, nurses and ECLS specialists), equipment resources and logistical planning.
体外生命支持 (ECLS) 是指使用血液灌注设备为心脏或呼吸系统提供高级支持。经皮血管插管插入、离心式泵技术和体外设备的小型化方面的进步使 ECLS 变得更加简单。本文的目的是讨论 ECLS 作为一种潜在的抢救方法,为急诊科 (ED) 临床医生在危急临床情况下提供支持,并重点关注在 ED 环境中管理 ECLS 计划的先决条件。
ED 中 ECLS 插管的可能适应证包括持续循环骤停、休克或难治性低氧血症和肺栓塞伴难治性休克。严重创伤、异物梗阻、低体温和近乎溺水等情况下,患者可能受益于 ECLS。ED 中的早期稳定可以为诊断性检查和/或紧急程序提供时间窗口,包括经皮冠状动脉介入、复温或创伤中的损伤控制性手术。ECLS 的使用需要大量资源,并且可能与并发症的高风险相关,尤其是在没有事先培训的情况下进行时。因此,只有在潜在问题可能可逆且有资源可用于解决器官功能障碍的病因时,才应使用 ECLS。
在面临危及生命的情况时,急诊紧急 ECLS 有其适应证。ECLS 为恢复、明确治疗、干预或手术提供了桥梁。ECLS 计划需要经过适当培训的工作人员(医生、护士和 ECLS 专家)、设备资源和后勤规划。