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心脏骤停后早期应用体外膜肺氧合以防止病情进一步恶化:综述与病例报告

Early Application of ECMO after Sudden Cardiac Arrest to Prevent Further Deterioration: A Review and Case Report.

作者信息

Kiss Boldizsár, Nagy Bettina, Pál-Jakab Ádám, Lakatos Bálint, Soltész Ádám, Osztheimer István, Heltai Krisztina, Édes István Ferenc, Németh Endre, Merkely Béla, Zima Endre

机构信息

Heart and Vascular Centre, Semmelweis University, Budapest 1122, Hungary.

出版信息

J Clin Med. 2023 Jun 25;12(13):4249. doi: 10.3390/jcm12134249.

Abstract

ECMO has become a therapeutic modality for in- and out-of-hospital scenarios and is also suitable as a bridging therapy until further decisions and interventions can be made. Case report: A 27-year-old male patient with mechanical aortic valve prothesis had a sudden cardiac arrest (SCA). ROSC had been achieved after more than 60 min of CPR and eight DC shocks due to ventricular fibrillation (VF). The National Ambulance Service unit transported the patient to our clinic for further treatment. Due to the trauma and therapeutic INR, a CT scan was performed and ruled out bleeding. Echocardiography described severely decreased left ventricular function. Coronary angiography was negative. Due to the therapeutic refractory circulatory and respiratory failure against intensive care, VA-ECMO implantation was indicated. After four days of ECMO treatment, the patient's circulation was stabilized without neurological deficit, and the functions of the end organs were normalized. Cardiac MRI showed no exact etiology behind SCA. ICD was implanted due to VF and SCA. The patient was discharged after 19 days of hospitalization. Conclusion: This case report points out that the early application of mechanical circulatory support could be an outcome-determinant therapeutic modality. Post-resuscitation care includes cardiorespiratory stabilization, treatment of reversible causes of malignant arrhythmia, and secondary prevention.

摘要

体外膜肺氧合(ECMO)已成为一种用于院内外情况的治疗方式,并且也适合作为一种过渡性治疗,直至能够做出进一步的决策和采取干预措施。病例报告:一名27岁男性患者,植入了机械主动脉瓣膜,发生了心脏骤停(SCA)。因室颤(VF),在进行了60多分钟心肺复苏(CPR)并给予8次直流电除颤后恢复了自主循环(ROSC)。国家救护服务单位将患者转运至我们的诊所进行进一步治疗。由于外伤和治疗性国际标准化比值(INR),进行了CT扫描,排除了出血。超声心动图显示左心室功能严重下降。冠状动脉造影结果为阴性。由于针对重症监护治疗难治的循环和呼吸衰竭,遂进行了静脉-动脉体外膜肺氧合(VA-ECMO)植入。经过4天的ECMO治疗,患者的循环稳定,无神经功能缺损,终末器官功能恢复正常。心脏磁共振成像(MRI)未显示心脏骤停的确切病因。因室颤和心脏骤停植入了植入式心律转复除颤器(ICD)。患者住院19天后出院。结论:本病例报告指出,早期应用机械循环支持可能是一种决定治疗结果的治疗方式。复苏后护理包括心肺稳定、治疗恶性心律失常的可逆病因以及二级预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02ac/10342643/0d1632e2eafb/jcm-12-04249-g001.jpg

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