Plaza Vicente, Giner Jordi, Calle Myriam, Rytilä Paula, Campo Carlos, Ribó Paula, Valero Antonio
From the Department of Respiratory Medicine, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomédica Sant Pau, Centro de Investigaciones Biomédicas en Red de Enfermedades Respiratorias, Universitat Autònoma de Barcelona, Barcelona, Spain.
Pulmonary Department, Hospital Clínico San Carlos, Department of Medicine, Faculty of Medicine, University Complutense of Madrid, Institute of Biomedical Research, Hospital Clínico San Carlos, Madrid, Spain.
Allergy Asthma Proc. 2018 Nov 18;39(6):437-444. doi: 10.2500/aap.2018.39.4183. Epub 2018 Oct 18.
Asthma guidelines recommend considering patient preferences for inhaler choice. However, few studies have assessed the impact of patient satisfaction with an inhaler on adherence and health outcomes. To assess the impact of patient satisfaction with an inhaler on adherence and health outcomes in asthma. In a cross-sectional, observational, multicenter study, 778 patients with moderate or severe asthma and who were treated with maintenance inhalers completed a number of scales and questionnaires: the Feeling of Satisfaction with Inhaler (FSI-10) questionnaire, the Treatment Satisfaction Questionnaire for Medication, the Test of Adherence to Inhalers (TAI), the Morisky-Green questionnaire, and the Asthma Control Test (ACT). The study population was categorized according to a median FSI-10 score as high (49.4%) and low (50.6%) satisfaction with their inhaler. Logistic regression analysis showed that high specific satisfaction with an inhaler was associated with the younger age group (odds ratio [OR] 0.976 [95% confidence interval {CI} 0.965-0.987]); male gender (OR 1.725 [95% CI 1.187-2.507]); controlled asthma: ACT score ≥ 20 (OR 1.664 [95% CI 1.133-2.445]); high general satisfaction with treatment (OR 4.861 [95% CI 3.335-7.085]); high adherence to inhaler: TAI score ≥ 46 (OR 1.546 [95% CI 1.025-2.332]); nonsevere asthma (OR 1.056 [95% CI 0.648-1.721]); and no trouble with inhaler use (OR 0.401 [95% CI 0.174-0.922]). High patient satisfaction with an inhaler, irrespective of received medication, was related to adherence and asthma control. Our results pointed out the relevance of inhaler choice in inhaled therapy; these results could be useful for designing new strategies targeted to increase adherence in patients with asthma.
哮喘指南建议在选择吸入器时考虑患者的偏好。然而,很少有研究评估患者对吸入器的满意度对依从性和健康结果的影响。为了评估患者对吸入器的满意度对哮喘患者依从性和健康结果的影响。在一项横断面、观察性、多中心研究中,778例中度或重度哮喘患者接受维持性吸入器治疗,他们完成了一些量表和问卷:吸入器满意度问卷(FSI - 10)、药物治疗满意度问卷、吸入器依从性测试(TAI)、Morisky - Green问卷和哮喘控制测试(ACT)。根据FSI - 10得分中位数,将研究人群分为对吸入器满意度高(49.4%)和低(50.6%)两组。逻辑回归分析表明,对吸入器的高特异性满意度与以下因素相关:较年轻的年龄组(比值比[OR] 0.976 [95%置信区间{CI} 0.965 - 0.987]);男性(OR 1.725 [95% CI 1.187 - 2.507]);哮喘得到控制:ACT得分≥20(OR 1.664 [95% CI 1.133 - 2.445]);对治疗的总体满意度高(OR 4.861 [95% CI 3.335 - 7.085]);对吸入器的高依从性:TAI得分≥46(OR 1.546 [95% CI 1.