Tietz Franziska, Adams Ines, Lücke Eva, Schreiber Jens
Department of Pneumonology, University Medicine, Magdeburg, Germany.
Department of Pediatrics, University Medicine, Magdeburg, Germany.
Patient Prefer Adherence. 2023 Apr 4;17:951-959. doi: 10.2147/PPA.S381486. eCollection 2023.
Inhalation therapy is the cornerstone of treatment of bronchial asthma. A patient-specific selection of inhalation devices is necessary, as preference for a device plays an important role in terms of error rates in handling and adherence to therapy. However, there is no industry-independent study providing information on children's preferences for common inhaler types. The aim of the present study was to investigate the preference of asthmatic children for inhaler types commonly used in Germany. The effects of age, gender and the type of school visited on device preferences as well as the frequency of patient education and the role of health care providers in the choice for an inhaler were investigated.
Eighty children were included in this prospective cross-sectional study (age: 10.87 ± 2.62 years). The analysis was based on a questionnaire and validated checklists. All participants tested the use of nine placebo inhalers (Breezhaler, Diskus, Respimat, Spiromax, Turbohaler, Autohaler, metered-dose inhaler, Easyhaler and Novolizer) in a randomized order. For each device, patients were asked to assess handling, rate different device characteristics and name the device they would prefer most or least.
The most favored device was the Novolizer. Moreover, the Spiromax scored highest in numerous categories such as suitability in emergencies and "easiest" device to use. Patient preferences with respect to the addressed inhaler features were not significantly related to age, gender or school type.
The Novolizer and the Spiromax showed higher preference in pediatric patients as compared to other tested devices. Overall, there were significant differences in terms of preference when comparing the tested inhalers in different aspects.
吸入疗法是支气管哮喘治疗的基石。由于患者对吸入装置的偏好对操作错误率和治疗依从性有重要影响，因此需要根据患者个体情况选择吸入装置。然而，尚无独立于行业的研究提供有关儿童对常见吸入器类型偏好的信息。本研究的目的是调查德国哮喘儿童对常用吸入器类型的偏好。研究了年龄、性别和就读学校类型对装置偏好的影响，以及患者教育的频率和医护人员在吸入器选择中的作用。
本前瞻性横断面研究纳入了80名儿童（年龄：10.87±2.62岁）。分析基于一份问卷和经过验证的清单。所有参与者以随机顺序测试了九种安慰剂吸入器（布地奈德都保、信必可都保、思力华能倍乐、准纳器、妥洛特罗都保、自动吸入器、定量吸入器、易纳器和诺富乐）的使用。对于每种装置，要求患者评估操作情况、对不同装置特性进行评分，并说出他们最喜欢或最不喜欢的装置。
最受欢迎的装置是诺富乐。此外，准纳器在许多类别中得分最高，如在紧急情况下的适用性和“最容易”使用的装置。患者对所提及的吸入器特征的偏好与年龄、性别或学校类型无显著相关性。
与其他测试装置相比，诺富乐和准纳器在儿科患者中表现出更高的偏好。总体而言，在不同方面比较测试的吸入器时，偏好存在显著差异。
