儿科脂肪肝疾病的研究进展：发病机制、诊断和治疗。
Advances in Pediatric Fatty Liver Disease: Pathogenesis, Diagnosis, and Treatment.
机构信息
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Emory University School of Medicine, 1760 Haygood Drive North East, Atlanta, GA 30322, USA.
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Emory University School of Medicine, 1760 Haygood Drive North East, Atlanta, GA 30322, USA; Division of Gastroenterology, Hepatology, and Nutrition, Children's Healthcare of Atlanta, 1405 Clifton Road, Atlanta, GA 30329, USA.
出版信息
Gastroenterol Clin North Am. 2018 Dec;47(4):949-968. doi: 10.1016/j.gtc.2018.07.016. Epub 2018 Sep 28.
Pediatric nonalcoholic fatty liver disease is an increasingly prevalent disease, but its pathophysiology is not fully elucidated, diagnosis is difficult and invasive, and therapeutic options are limited. This article addresses the recent advancements made in understanding the pathophysiology of nonalcoholic fatty liver disease, the development of less invasive diagnostic modalities, and emerging therapeutic options, including ongoing clinical trials in children.
小儿非酒精性脂肪性肝病是一种日益流行的疾病，但它的病理生理学尚未完全阐明，诊断困难且具有侵袭性，治疗选择有限。本文介绍了在理解非酒精性脂肪性肝病的病理生理学、开发侵入性较小的诊断方法以及新兴治疗选择方面的最新进展，包括正在进行的儿童临床试验。
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