Bourinet V, Thiam K, Guinde J, Laroumagne S, Dutau H, Astoul P
Service d'oncologie thoracique, maladies de la Plèvre, pneumologie interventionnelle, hôpital Nord Aix-Marseille université, 13000 Marseille, France.
Service d'oncologie thoracique, maladies de la Plèvre, pneumologie interventionnelle, hôpital Nord Aix-Marseille université, 13000 Marseille, France; Service de pneumo-oncologie, université Cheikh-Anta-Diop, CHU Fann, Dakar, Sénégal.
Rev Mal Respir. 2019 Jan;36(1):49-56. doi: 10.1016/j.rmr.2018.01.015. Epub 2018 Oct 16.
Benign laryngotracheal stenosis is a rare pathology with multiple etiologies, the management of which is complex. This is because of the configuration and proximity of the larynx and the difficulty with surgical approaches, which are potentially mutilating, especially for the management of a benign disease. When surgery is challenging, iterative dilatations of the stricture or the fashioning of a definitive tracheotomy are therapeutic alternatives. Advances in rigid bronchoscopy and the evolution of prosthetic silicone material allow a new approach in the management of benign laryngotracheal stenosis, by placing flexible silicone prostheses which cover all the stenosis from the arytenoids to the trachea. This preliminary work aims to evaluate the feasibility, effectiveness, tolerance and complications of the implementation of this type of prosthesis.
This is a retrospective single-centre study which analyzed the records of patients with symptomatic benign laryngotracheal stenosis who underwent placement of a transcordial prosthesis over a period of three years. The prosthesis used, inserted under general anesthesia during a rigid tube interventional bronchoscopy, was either a straight silicone prosthesis or a Montgomery T-tube for those with a pre-existing tracheotomy.
Six patients were included. Five are still alive, one patient died from a cause unrelated to the placement of the prosthesis. Four have no tracheostomy and two now have no transcordal prosthesis. The data collected on tolerance found, for three patients, two cases of minor aspiration and one case of transient cough. All patients had whispered voice dysphonia. We did not observe prosthesis migration or obstruction.
These preliminary results are encouraging. Transcordal prostheses in benign laryngotracheal stenosis have a complementary or alternative role compared to surgery with a palliative or even curative objective.
良性喉气管狭窄是一种病因多样的罕见病症,其治疗较为复杂。这是由于喉部的结构和位置关系,以及手术入路存在困难,手术可能具有致残性,尤其是对于良性疾病的治疗。当手术具有挑战性时,反复扩张狭窄部位或形成永久性气管切开术是治疗选择。硬质支气管镜技术的进步和人工硅胶材料的发展,使得通过放置可覆盖从杓状软骨到气管所有狭窄部位的柔性硅胶假体,为良性喉气管狭窄的治疗提供了一种新方法。这项初步研究旨在评估这类假体植入的可行性、有效性、耐受性及并发症。
这是一项回顾性单中心研究,分析了在三年期间接受经声门假体植入的有症状良性喉气管狭窄患者的记录。所使用的假体在硬质支气管镜介入下全身麻醉时插入,对于未行气管切开术的患者使用直硅胶假体,对于已有气管切开术的患者使用蒙哥马利T型管。
纳入6例患者。5例仍存活,1例患者死于与假体植入无关的原因。4例未行气管造口术,2例目前已无经声门假体。关于耐受性收集的数据显示,3例患者中,2例有轻微误吸,1例有短暂咳嗽。所有患者均有耳语性发声障碍。未观察到假体移位或阻塞。
这些初步结果令人鼓舞。良性喉气管狭窄的经声门假体与具有姑息甚至治愈目的的手术相比,具有补充或替代作用。