Yan W J, Zheng J J, Chen X X
First Clinical Division, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100034, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2018 Oct 18;50(5):911-914.
To evaluate the clinical effect of fluoride releasing flowable resin used in treatment of early enamel caries of children compared with conventional sealant.
Seventy-six patients, including fifty-two couples of permanent first molars and thirty couples of premolars were selected for this trial. Both sides of all the molars and premolars were diagnosed as early enamel caries based on International Caries Detection and Assessment System (ICDAS) dental caries diagnostic criteria. Using the contralateral control, the teeth were randomly divided into two groups. Molars/premolars in the experimental group were sealed with a fluoride releasing flowable resin; the contralateral molars/premolars were sealed with a conventional fissure sealant as a control group. The retention rate and progress of caries were evaluated at the end of 3, 6, 12 and 24 months.
There was no fissure sealant loss or caries progression in both groups 3 and 6 months after sealing the premolars by fluoride releasing flowable resin or conventional fissure sealants. At the end of 12 and 24 months, only one case of fissure sealant loss was observed in conventional fissure sealant group. There was no statistical significance between the two premolar groups. In the first molar group, fluoride releasing flowable resin showed 100%, 98.08%, 90.38% and 88.46% complete retention at the end of 3, 6, 12 and 24 months, respectively. The conventional fissure sealant retention rates were 96.15%, 92.31%, 76.92% and 73.08% at the corresponding time points. The data at the end of 24 months showed that fluoride releasing flowable resin had significantly higher retention rate than the conventional fissure sealant group (P<0.05). The incidence of caries progression at the end of 6, 12 and 24 months were 1.92%, 5.77% and 7.69%, respectively, in the fluoride releasing flowable resin group. In the conventional fissure sealant group, the incidence was 5.77%, 19.23% and 25.00%, respectively. At the end of 12 and 24 months, more significant decrease of caries progress incidence was observed in the fluoride releasing flowable resin group than in the control group, and there was statistical difference between the two groups (P<0.05).
Compared with conventional fissure sealant, using fluoride releasing flowable resin as a fissure sealant in children enamel caries of permanent molars can improve the sealant preservation rate and effectively prevent enamel caries progress.
评估释放氟的可流动树脂用于治疗儿童早期釉质龋的临床效果，并与传统窝沟封闭剂作比较。
选取76例患者，包括52对恒第一磨牙和30对前磨牙进行本试验。根据国际龋病检测与评估系统（ICDAS）龋病诊断标准，所有磨牙和前磨牙的两侧均被诊断为早期釉质龋。采用对侧对照，将牙齿随机分为两组。实验组的磨牙/前磨牙用释放氟的可流动树脂进行窝沟封闭；对侧的磨牙/前磨牙用传统窝沟封闭剂进行封闭作为对照组。在3、6、12和24个月结束时评估封闭剂的保留率和龋病进展情况。
用释放氟的可流动树脂或传统窝沟封闭剂封闭前磨牙后3个月和6个月，两组均未出现窝沟封闭剂脱落或龋病进展。在12个月和24个月结束时，传统窝沟封闭剂组仅观察到1例窝沟封闭剂脱落。两个前磨牙组之间无统计学意义。在第一磨牙组中，释放氟的可流动树脂在3、6、12和24个月结束时的完全保留率分别为100%、98.08%、90.38%和88.46%。相应时间点传统窝沟封闭剂的保留率分别为96.15%、92.31%、76.92%和73.08%。24个月结束时的数据显示，释放氟的可流动树脂的保留率显著高于传统窝沟封闭剂组（P<0.05）。释放氟的可流动树脂组在6、12和24个月结束时的龋病进展发生率分别为1.92%、5.77%和7.69%。在传统窝沟封闭剂组中，发生率分别为5.77%、19.23%和25.00%。在12个月和24个月结束时，释放氟的可流动树脂组的龋病进展发生率比对照组有更显著的下降，两组之间有统计学差异（P<0.05）。
与传统窝沟封闭剂相比，在儿童恒磨牙釉质龋中使用释放氟的可流动树脂作为窝沟封闭剂可提高封闭剂保存率并有效预防釉质龋进展。
