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针对不同的准直器和加速器生成的调强放射治疗/容积调强弧形治疗剂量分布。 (你提供的原文中“for and collimators and accelerators”部分内容缺失,我根据常见情况补充了“不同的”来使句子完整通顺,你可根据实际情况修改。)

IMRT/VMAT dose distributions generated for and collimators and accelerators.

作者信息

Ślosarek Krzysztof, Brąclik Iwona, Leszczyński Wojciech, Kopczyńska Joanna, Osewski Wojciech, Wendykier Jacek

机构信息

Radiotherapy Planning Department, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology Gliwice Branch, Wybrzeże Armii Krajowej 15, 44-100 Gliwice, Poland.

IT Department, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology Gliwice Branch, Wybrzeże Armii Krajowej 15, 44-100 Gliwice, Poland.

出版信息

Rep Pract Oncol Radiother. 2019 Jan-Feb;24(1):20-27. doi: 10.1016/j.rpor.2018.09.001. Epub 2018 Oct 10.

DOI:10.1016/j.rpor.2018.09.001
PMID:30337844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6187085/
Abstract

AIM

The aim of this study is to answer the question whether the calculated dose distributions for HD and Millennium collimators (Varian Medical Systems) are equivalent for large treatment volumes.

BACKGROUND

Modern biomedical linacs are equipped with multileaf collimators where leaves can be of different widths. Thinner leaves allow better fit to desired (tumor) shape. At the same time, however, the maximum size of the field that can be obtained with the collimator is also reduced. Varian Medical Systems HD and Millennium collimators can be a good sample. They have 40 cm or 22 cm × 40 cm maximal field size at the isocenter, respectively.

MATERIALS AND METHODS

This paper presents the comparison of selected statistical and dosimetric parameters achieved for treatment plans where the beams for a HD collimator had to be merged because of the size of the tumor volume.

RESULTS AND DISCUSSION

Achieved results show that, independently from irradiated volume, there is no statistically significant difference for calculated dose distributions, integral doses, MU values and coefficients evaluating dose distributions for HD and Millennium collimators.

CONCLUSIONS

Results show that both types of collimators can be used interchangeably for preparing the treatment plans for large tumor volume without quality reduction of the prepared treatment plan.

摘要

目的

本研究旨在回答对于大治疗体积而言,瓦里安医疗系统公司的HD准直器和 Millennium 准直器的计算剂量分布是否等效这一问题。

背景

现代生物医学直线加速器配备有多叶准直器,其中叶片宽度可以不同。较薄的叶片能更好地拟合期望的(肿瘤)形状。然而,与此同时,使用准直器可获得的最大射野尺寸也会减小。瓦里安医疗系统公司的HD准直器和 Millennium 准直器可以作为一个很好的样本。它们在等中心处的最大射野尺寸分别为40 cm或22 cm×40 cm。

材料与方法

本文展示了对因肿瘤体积大小而必须合并HD准直器射束的治疗计划所获得的选定统计和剂量学参数的比较。

结果与讨论

所获得的结果表明,无论照射体积如何,HD准直器和 Millennium 准直器的计算剂量分布、积分剂量、MU值以及评估剂量分布的系数均无统计学显著差异。

结论

结果表明,在为大肿瘤体积准备治疗计划时,这两种类型的准直器可以互换使用,而不会降低所准备治疗计划的质量。

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本文引用的文献

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Comparison of treatment planning parameters for dose painting head and neck plans delivered with tomotherapy.螺旋断层放疗用于头颈部剂量调强计划的治疗计划参数比较。
Br J Radiol. 2016;89(1060):20150970. doi: 10.1259/bjr.20150970. Epub 2016 Feb 1.
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A three-field monoisocentric inverse breast treatment planning technique without half-beam blocking.一种无半束阻挡的三野单等中心乳腺逆向治疗计划技术。
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Integral dose and radiation-induced secondary malignancies: comparison between stereotactic body radiation therapy and three-dimensional conformal radiotherapy.积分剂量与放射诱导的继发性恶性肿瘤:立体定向体部放射治疗与三维适形放射治疗的比较。
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Radiother Oncol. 2009 Apr;91(1):42-8. doi: 10.1016/j.radonc.2008.11.016. Epub 2009 Feb 3.
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Intensity modulated radiation therapy with multileaf collimators of different leaf widths: a comparison of achievable dose distributions.不同叶宽多叶准直器的调强放射治疗:可实现剂量分布的比较
Radiother Oncol. 2005 Apr;75(1):106-11. doi: 10.1016/j.radonc.2005.02.007. Epub 2005 Apr 18.
7
Impact of IMRT and leaf width on stereotactic body radiotherapy of liver and lung lesions.调强放疗及叶片宽度对肝脏和肺部病变立体定向体部放疗的影响。
Int J Radiat Oncol Biol Phys. 2005 Apr 1;61(5):1572-81. doi: 10.1016/j.ijrobp.2004.12.075.
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Comparison of a micro-multileaf collimator with a 5-mm-leaf-width collimator for intracranial stereotactic radiotherapy.用于颅内立体定向放射治疗的微型多叶准直器与5毫米叶宽准直器的比较。
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Med Phys. 1999 Jul;26(7):1212-21. doi: 10.1118/1.598615.
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Impact of collimator leaf width on stereotactic radiosurgery and 3D conformal radiotherapy treatment plans.准直器叶片宽度对立体定向放射外科和三维适形放射治疗计划的影响。
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