Asa Sylvia L, Mete Ozgur
Department of Pathology, University Health Network, Toronto, ON, Canada.
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Front Endocrinol (Lausanne). 2018 Sep 25;9:555. doi: 10.3389/fendo.2018.00555. eCollection 2018.
Thyroid tumors usually present as masses in the thyroid gland. While the majority of these tumors represent neoplasms of thyroid tissues, mainly of follicular epithelial cell differentiation, the differential diagnosis includes other lesions, such as C cell neoplasms (medullary thyroid carcinoma), intrathyroidal parathyroid, or thymic tumors, soft tissue tumors, and hematologic neoplasms as well as metastatic malignancies. Rare tumors are of salivary gland types. This case illustrates an unusual tumor of salivary gland type, an intrathyroidal mammary analog secretory carcinoma (MASC). The pathogenesis, diagnostic pitfalls, and therapeutic implications of this unusual tumor are discussed.
甲状腺肿瘤通常表现为甲状腺内的肿块。虽然这些肿瘤大多数是甲状腺组织的肿瘤,主要是滤泡上皮细胞分化型,但鉴别诊断还包括其他病变,如C细胞肿瘤(甲状腺髓样癌)、甲状腺内甲状旁腺或胸腺肿瘤、软组织肿瘤、血液系统肿瘤以及转移性恶性肿瘤。罕见的肿瘤为唾液腺类型。本病例展示了一种不寻常的唾液腺型肿瘤,即甲状腺内乳腺类似物分泌性癌(MASC)。本文讨论了这种不寻常肿瘤的发病机制、诊断陷阱及治疗意义。