Juarez Marisa Danielle
Texas Children's Hospital, Houston, TX, United States.
Front Pediatr. 2018 Oct 4;6:267. doi: 10.3389/fped.2018.00267. eCollection 2018.
Children with end-stage renal disease (ESRD) on hemodialysis are at increased risk for malnutrition. Aggressive nutrition intervention such as intradialytic parenteral nutrition (IDPN) should be considered to prevent further co-morbidities and mortality associated with malnutrition when other interventions fail. IDPN is a non-invasive method of providing nutrition to malnourished hemodialysis (HD) patients via the HD access throughout the HD treatment. Although the evidence on the long-term benefits of IDPN is scant in pediatrics, there is evidence that it improves metabolic parameters and nutritional status. In this paper, therapy with IDPN including indications, goals of therapy, and elements to monitor will be described. In addition, a practice guideline for prescribing IDPN is provided.
接受血液透析的终末期肾病(ESRD)儿童发生营养不良的风险增加。当其他干预措施无效时,应考虑采取积极的营养干预措施,如透析期间肠外营养(IDPN),以预防与营养不良相关的进一步合并症和死亡。IDPN是一种通过血液透析通路在整个血液透析治疗过程中为营养不良的血液透析(HD)患者提供营养的非侵入性方法。尽管儿科领域关于IDPN长期益处的证据很少,但有证据表明它能改善代谢参数和营养状况。本文将描述IDPN治疗,包括适应症、治疗目标和监测要点。此外,还提供了IDPN处方的实践指南。