Morita T, Kondo S, Dohkita S, Tsuchida S
Tohoku J Exp Med. 1987 Feb;151(2):201-4. doi: 10.1620/tjem.151.201.
The effects of forskolin and isoproterenol on contractile force and cyclic AMP (cAMP) levels were compared in rabbit detrusor. Both forskolin and isoproterenol produced relaxation of rabbit detrusor and an increase in cAMP levels in the tissue. Although the relaxant response to forskolin was similar to that of isoproterenol, the increase in cAMP levels induced by forskolin was significantly larger than that induced by isoproterenol. These results suggest that there is a discrepancy in the relaxation responses and cAMP levels in response to forskolin and isoproterenol.
在兔逼尿肌中比较了福斯高林和异丙肾上腺素对收缩力和环磷酸腺苷（cAMP）水平的影响。福斯高林和异丙肾上腺素均使兔逼尿肌松弛，并使组织中的cAMP水平升高。尽管福斯高林的舒张反应与异丙肾上腺素相似，但福斯高林诱导的cAMP水平升高显著大于异丙肾上腺素诱导的升高。这些结果表明，福斯高林和异丙肾上腺素引起的舒张反应和cAMP水平存在差异。
