Newborn Research, Royal Women's Hospital, Parkville, VIC, Australia; Victorian Infant Brain Studies, Clinical Sciences, Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, VIC, Australia.
Victorian Infant Brain Studies, Clinical Sciences, Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Developmental Imaging, Murdoch Children's Research Institute, Melbourne, Australia; Florey Institute of Neuroscience and Mental Health, Melbourne, Australia.
Semin Fetal Neonatal Med. 2019 Feb;24(1):60-65. doi: 10.1016/j.siny.2018.10.003. Epub 2018 Oct 14.
With increasing evidence of neurodevelopmental problems faced by late preterm children, there is a need to explore possible underlying brain structural changes. The use of brain magnetic resonance imaging has provided insights of smaller and less mature brains in infants born late preterm, associated with developmental delay at 2 years. Another useful tool in the newborn period is neurobehavioural assessment, which has also been shown to be suboptimal in late preterm infants compared with tern infants. Suboptimal neurobehaviour is also associated with poorer 2-year neurodevelopment in late preterm infants. More research into these tools will provide a better understanding of the underlying processes of developmental deficits of late preterm children. The value of their role in clinical care remains to be determined.
随着越来越多的证据表明晚期早产儿面临神经发育问题，有必要探索潜在的大脑结构变化。脑磁共振成像的应用提供了早产儿出生时大脑较小且不成熟的见解，与 2 岁时的发育迟缓有关。新生儿期另一个有用的工具是神经行为评估，与足月婴儿相比，晚期早产儿的神经行为评估也不理想。神经行为不佳也与晚期早产儿 2 岁时神经发育较差有关。对这些工具的进一步研究将有助于更好地了解晚期早产儿发育缺陷的潜在过程。它们在临床护理中的作用价值仍有待确定。
