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在随后发展为脑瘫的新生儿重症监护病房毕业生中的新生儿神经影像学研究。

Neonatal Neuroimaging in Neonatal Intensive Care Graduates Who Subsequently Develop Cerebral Palsy.

作者信息

Battin Malcolm R, Williams Sîan A, Mackey Anna, Alzaher Woroud, Sorhage Alexandra, Stott N Susan

机构信息

Newborn Services, Auckland City Hospital, Park Road, Grafton, Auckland 1023, New Zealand.

Liggins Institute, University of Auckland, Park Road, Grafton, Auckland 1142, New Zealand.

出版信息

J Clin Med. 2022 Mar 28;11(7):1866. doi: 10.3390/jcm11071866.

DOI:10.3390/jcm11071866
PMID:35407475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9000159/
Abstract

Cerebral palsy is a common cause of physical disability. The New Zealand Cerebral Palsy Register (NZCPR) was established in 2015 and reports national data. Internationally, an early CP diagnosis has been a focus, with imaging and clinical tools used to enable early accurate detection. Accordingly, guidelines are being developed for New Zealand, including a specific pathway for high-risk neonatal intensive care (NICU) graduates, reflecting the high rate of CP in this group. To inform this work, we reviewed imaging data from a retrospective NICU cohort identified from the NZCPR. In these 140 individuals with CP and a confirmed NICU admission during 2000-2019 inclusive, imaging frequency, modality, and rate of abnormality was determined. Overall, 114 (81.4%) had imaging performed in the NICU, but the frequency and modality used varied by gestational subgroup. For infants born at less than 32 weeks gestation, 53/55 had routine imaging with ultrasound, and IVH was graded as none or mild (grade 1-2) in 35 or severe (grade 3-4) in 18 infants. For the 34 infants born between 32-36 weeks gestation, only 13/19 imaged in the NICU were reported as abnormal. For 51 term-born infants, 41/42 imaged in the NICU with MRI had abnormal results.

摘要

脑瘫是身体残疾的常见原因。新西兰脑瘫登记册(NZCPR)于2015年建立并报告全国数据。在国际上,早期脑瘫诊断一直是一个重点,人们使用影像学和临床工具来实现早期准确检测。因此,新西兰正在制定相关指南,包括针对高危新生儿重症监护病房(NICU)出院患儿的特定路径,这反映了该群体中脑瘫的高发病率。为了为这项工作提供信息,我们回顾了从NZCPR中确定的一个回顾性NICU队列的影像学数据。在这140名确诊为脑瘫且在2000年至2019年(含)期间确诊入住过NICU的个体中,确定了影像学检查的频率、方式和异常率。总体而言,114人(81.4%)在NICU进行了影像学检查,但使用的频率和方式因孕周亚组而异。对于孕周小于32周出生的婴儿,55人中有

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/131b/9000159/bad049af4e4a/jcm-11-01866-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/131b/9000159/bad049af4e4a/jcm-11-01866-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/131b/9000159/bad049af4e4a/jcm-11-01866-g001.jpg

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本文引用的文献

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