Sozzi G, Bertoglio M G, Borrello M G, Gianì S, Pilotti S, Pierotti M, Della Porta G
Cancer Genet Cytogenet. 1987 Jul;27(1):45-50. doi: 10.1016/0165-4608(87)90259-7.
A cytogenetic analysis of a fresh primary tumor specimen of small cell lung cancer showed a del(3)(p14p23) in the majority of metaphases. Additional clonal changes were found in the karyotype. No abnormalities for Ha-ras, Ki-ras, N-ras, myb, or myc were detected by Southern blot analysis of the tumor DNA.
对一份新鲜的小细胞肺癌原发性肿瘤标本进行的细胞遗传学分析显示，在大多数中期相中存在del(3)(p14p23)。在核型中还发现了其他克隆性改变。通过对肿瘤DNA进行Southern印迹分析，未检测到Ha-ras、Ki-ras、N-ras、myb或myc有异常。
