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采用二因素设计研究静电纺丝工艺变量对聚合物纤维尺寸及串珠结构的影响。

Effect of electrospinning process variables on the size of polymer fibers and bead-on-string structures established with a 2 factorial design.

作者信息

Korycka Paulina, Mirek Adam, Kramek-Romanowska Katarzyna, Grzeczkowicz Marcin, Lewińska Dorota

机构信息

Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.

出版信息

Beilstein J Nanotechnol. 2018 Sep 17;9:2466-2478. doi: 10.3762/bjnano.9.231. eCollection 2018.

DOI:10.3762/bjnano.9.231
PMID:30345211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6176837/
Abstract

This work examines the effect of selected process parameters on the diameter of uniform and heterogeneous fibers (with and without bead-on-string structures) and the size of beads obtained during the electrospinning process. A 2 factorial design was performed to determine the influence of the following factors: electrical voltage, flow rate and dynamic viscosity of the poly(vinylpyrrolidone) ethanolic solution. Factorial design enables the analysis of the mathematical relationship between the chosen factors and the response with a minimum number of experiments. The factor having the most significant impact on the size of beaded fibers and beads was the solution viscosity, while the voltage had the greatest influence on the bead-free fiber diameter. The interactions between the studied factors were also analyzed. It was found that the presented method can be used for the design of an optimal and cost-effective electrospinning process, allowing the desired product to be obtained with expected features.

摘要

本研究考察了电纺丝过程中选定工艺参数对均匀和非均匀纤维（有无串珠结构）直径以及所得珠子尺寸的影响。采用二因子设计来确定以下因素的影响：电压、流速和聚乙烯吡咯烷酮乙醇溶液的动态粘度。因子设计能够以最少的实验次数分析所选因素与响应之间的数学关系。对串珠纤维和珠子尺寸影响最显著的因素是溶液粘度，而电压对无珠纤维直径影响最大。还分析了所研究因素之间的相互作用。结果表明，该方法可用于设计优化且经济高效的电纺丝工艺，从而获得具有预期特性的所需产品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/841fbb9acf24/Beilstein_J_Nanotechnol-09-2466-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/7271deef6774/Beilstein_J_Nanotechnol-09-2466-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/7a8a5e369eaa/Beilstein_J_Nanotechnol-09-2466-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/8c2075d25a19/Beilstein_J_Nanotechnol-09-2466-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/107b8c0cf2f6/Beilstein_J_Nanotechnol-09-2466-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/e69977bc3f9a/Beilstein_J_Nanotechnol-09-2466-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/6c192091d8cf/Beilstein_J_Nanotechnol-09-2466-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/9a27e234c302/Beilstein_J_Nanotechnol-09-2466-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/4f5cbac592c9/Beilstein_J_Nanotechnol-09-2466-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/7742cabb02fd/Beilstein_J_Nanotechnol-09-2466-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/14072442e569/Beilstein_J_Nanotechnol-09-2466-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/3f6429b2725c/Beilstein_J_Nanotechnol-09-2466-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/e6b9bb86a87c/Beilstein_J_Nanotechnol-09-2466-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/841fbb9acf24/Beilstein_J_Nanotechnol-09-2466-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/7271deef6774/Beilstein_J_Nanotechnol-09-2466-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/7a8a5e369eaa/Beilstein_J_Nanotechnol-09-2466-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/8c2075d25a19/Beilstein_J_Nanotechnol-09-2466-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/107b8c0cf2f6/Beilstein_J_Nanotechnol-09-2466-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/e69977bc3f9a/Beilstein_J_Nanotechnol-09-2466-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/6c192091d8cf/Beilstein_J_Nanotechnol-09-2466-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/9a27e234c302/Beilstein_J_Nanotechnol-09-2466-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/4f5cbac592c9/Beilstein_J_Nanotechnol-09-2466-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/7742cabb02fd/Beilstein_J_Nanotechnol-09-2466-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/14072442e569/Beilstein_J_Nanotechnol-09-2466-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/3f6429b2725c/Beilstein_J_Nanotechnol-09-2466-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/e6b9bb86a87c/Beilstein_J_Nanotechnol-09-2466-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efcd/6176837/841fbb9acf24/Beilstein_J_Nanotechnol-09-2466-g014.jpg

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