NaYbF@CaF 核壳上转换纳米粒子的一锅法合成及其对谷胱甘肽的灵敏检测。
NaYbF@CaF core-satellite upconversion nanoparticles: one-pot synthesis and sensitive detection of glutathione.
机构信息
Department of Materials Science and Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR, China.
出版信息
Nanoscale. 2018 Nov 1;10(42):19898-19905. doi: 10.1039/c8nr05552a.
A new class of core-satellite upconversion nanoparticles (UCNPs) formed through a kinetically controlled oriented attachment is presented. The core-satellite UCNPs comprising an optically active α-NaYbF4 core and several CaF2 satellites are synthesized by a one-pot sequential injection technique. Compared to conventional core-shell UCNPs, these core-satellite UCNPs show larger surface-to-volume ratios and are suitable for further surface modifications. As a proof-of-concept, a biosensing system is constructed by coating MnO2 nanosheets on the α-NaYbF4:Tm@CaF2 core-satellite UCNPs for high-sensitivity biothiol detection. These core-satellite UCNPs show great potential in the development of UCNP-based nanohybrids for biosensing, multimodal imaging and drug delivery.
一种通过动力学控制的定向附着形成的新型核-壳上转换纳米粒子（UCNPs）被提出。这些由具有光学活性的α-NaYbF4 核和几个 CaF2 卫星组成的核-壳 UCNPs 通过一锅顺序注入技术合成。与传统的核壳 UCNPs 相比，这些核-壳 UCNPs 具有更大的表面积与体积比，适合进一步的表面修饰。作为一个概念验证，通过在α-NaYbF4:Tm@CaF2 核-壳 UCNPs 上包覆 MnO2 纳米片构建了一个用于高灵敏度生物硫醇检测的生物传感系统。这些核-壳 UCNPs 在开发基于 UCNP 的用于生物传感、多模态成像和药物输送的纳米杂化材料方面具有巨大的潜力。
Zotero 插件