Department of Clinical Immunology and Internal Medicine, National Reference Center for Autoimmune Diseases (RESO), Referral Centre for Primary Immunodeficiencies, Strasbourg University Hospital, 67091 Strasbourg, France; CNRS UPR 3572, Immunopathology and Therapeutic Chemistry, Strasbourg University, 67000 Strasbourg, France; UFR Médecine, Université de Strasbourg, 67000 Strasbourg, France.
Department of Clinical Immunology and Internal Medicine, National Reference Center for Autoimmune Diseases (RESO), Referral Centre for Primary Immunodeficiencies, Strasbourg University Hospital, 67091 Strasbourg, France.
Clin Immunol. 2018 Dec;197:198-204. doi: 10.1016/j.clim.2018.10.010. Epub 2018 Oct 19.
Adolescence is a time of physical, psychological and social changes between childhood and adulthood. All adolescents and young adults (AYAs) are in transition and experience key underlying processes that will influence their later life. It is a critical period, particularly for AYAs with a chronic medical condition. Diseases can start at any point during adolescence. The transition of care will concern health care providers, as well as more unexpected actors such as social workers, teachers, business managers and the family. In this review, we focus on transition in primary immunodeficiencies (PIDs) and autoimmune diseases (AIDs). We describe the challenges and needs of transition in the field. Questions that AYAs with PID and/or AID must face during transition in their familial, professional and personal life are discussed. We expose a practical, AYA centered approach to help physicians in their daily practice, and we propose a position for the future.
青春期是儿童期向成年期过渡的生理、心理和社会变化时期。所有青少年和年轻人（AYAs）都在过渡中，经历着将影响他们以后生活的关键潜在过程。这是一个关键时期，特别是对于患有慢性疾病的 AYAs 来说。疾病可能在青春期的任何时候开始。这种医疗护理的转变将涉及医疗保健提供者，以及更意想不到的角色，如社会工作者、教师、企业经理和家庭。在这篇综述中，我们重点关注原发性免疫缺陷（PID）和自身免疫性疾病（AIDs）的过渡。我们描述了该领域过渡所面临的挑战和需求。讨论了 PID 和/或 AID 的 AYAs 在家庭、专业和个人生活中过渡时必须面对的问题。我们提出了一种以 AYA 为中心的实用方法来帮助医生在日常实践中，并提出了未来的立场。
