Saigal Renu, Bhakal Surendra Singh, Goyal Laxmikant, Goel Akhil D
Professor and Head, Department of Medicine, Jaipur National University IMSRC, Jaipur, Rajasthan, Former Senior Professor and Head, Department of Medicine, Former In-Charge Rheumatology Services, SMS Medical College, Jaipur, Rajasthan.
Former Resident.
J Assoc Physicians India. 2018 Apr;66(4):26-8.
To evaluate the prevalence of anti- citrullinated protein antibodies (ACPA) in patients with a variety of rheumatic diseases other than rheumatoid arthritis (RA).
144 cases of rheumatic diseases other than rheumatoid arthritis (RA) over a period of 1 year were recruited after consenting and followed up for 2 years. Their serum samples were tested for ACPA.
ACPA seropositivity of 9.03% was observed in rheumatic diseases other than RA.
Whether ACPA seropositivity in non-RA rheumatic diseases indicates a false positive result or an overlap RA syndrome is a mystery yet unsolved. Long term follow ups of these patients will be required to understand the course of rheumatic diseases in relation to ACPA..
评估类风湿关节炎（RA）以外的多种风湿性疾病患者中抗瓜氨酸化蛋白抗体（ACPA）的患病率。
在获得同意后，招募了144例1年内患类风湿关节炎（RA）以外风湿性疾病的患者，并进行了2年的随访。检测他们的血清样本中的ACPA。
在类风湿关节炎（RA）以外的风湿性疾病中，观察到ACPA血清阳性率为9.03%。
非类风湿关节炎（RA）风湿性疾病中的ACPA血清阳性是假阳性结果还是重叠性RA综合征，仍是一个未解之谜。需要对这些患者进行长期随访，以了解与ACPA相关的风湿性疾病病程。
