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射频消融治疗转移性肝肿瘤后发生急性心包炎:一例报告

Acute pericarditis following treatment of a metastatic liver tumor with radiofrequency ablation: a case report.

作者信息

Hsu Jung-Chi, Tsai Han-Lin, Lin Yu-Ling, Chang Rei-Yeuh

机构信息

Division of Cardiology, Department of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, 539 Jhongsiao Road, Chia-Yi, 60002, Taiwan.

Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.

出版信息

BMC Cardiovasc Disord. 2018 Oct 22;18(1):200. doi: 10.1186/s12872-018-0937-7.

Abstract

BACKGROUND

Radiofrequency ablation is a common and minimally invasive procedure used to treat liver tumors. However, the potential threat of heat injury to adjacent structures if the hepatic lesion is near the diaphragm is often overlooked and misunderstood. Rare cardiovascular complications have been reported. How best to identify the patients at risk to allow for prompt treatment is an important issue.

CASE PRESENTATION

A 56-year-old man with underlying oral cancer received radiofrequency ablation for a metastatic liver tumor at segment II. Pleuritic chest pain developed on the day after radiofrequency catheter ablation. Diffuse ST elevation and echocardiography showed the new onset of small to moderate pericardial effusion without tamponade sign. Inflammatory markers were also elevated. Acute pericarditis due to heat penetration and stimulation was favored. His symptoms and signs resolved after treatment with anti-inflammatory medication.

CONCLUSION

Potential cardiovascular complications are possible after radiofrequency catheter ablation for liver tumors located at segment II. Artificial ascites with normal saline before radiofrequency ablation may separate the liver and diaphragm to prevent cardiac complications. During the procedure, electrocardiographic monitoring and close observation of the patient's symptom are required. Echocardiography can be used to confirm cardiac complications.

摘要

背景

射频消融是一种用于治疗肝肿瘤的常见微创治疗方法。然而,如果肝脏病变靠近膈肌,热损伤对邻近结构的潜在威胁常常被忽视和误解。已有罕见心血管并发症的报道。如何最好地识别有风险的患者以便及时治疗是一个重要问题。

病例介绍

一名患有口腔癌的56岁男性因肝Ⅱ段转移瘤接受了射频消融治疗。射频导管消融术后第二天出现胸膜炎性胸痛。弥漫性ST段抬高及超声心动图显示新出现少量至中等量心包积液,无心脏压塞征象。炎症标志物也升高。考虑为热穿透和刺激导致的急性心包炎。经抗炎药物治疗后,其症状和体征消失。

结论

对于位于肝Ⅱ段的肿瘤进行射频导管消融后可能出现潜在的心血管并发症。射频消融前用生理盐水制造人工腹水可使肝脏与膈肌分离,预防心脏并发症。术中需要进行心电图监测并密切观察患者症状。超声心动图可用于确诊心脏并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01f/6198527/8f9baebebc21/12872_2018_937_Fig1_HTML.jpg

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