State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Talanta. 2019 Jan 15;192:387-394. doi: 10.1016/j.talanta.2018.08.042. Epub 2018 Aug 29.
A graphene modified glassy carbon electrode was fabricated for sensitive and convenient electrochemical detection of 1-hydroxypyrene (1-OHP). The graphene modified electrode was prepared by eletrochemical reduction of graphene oxide on glass carbon electrode. l-OHP was synergistically accumulated on the graphene modified electrode via π-π conjugate adsorption and electrochemical oxidation. Electrochemical behavior of l-OHP on the graphene modified glass carbon electrode was studied in detail. The developed method gave a linear calibration curve for the determination of 1-OHP in the range of 5-300 nM (R = 0.997), a limit of detection of 0.84 nM (S/N = 3). The proposed method was also successfully applied to the analysis of urine samples for l-OHP with the recoveries of 97.3-101.1%.
一种基于石墨烯修饰的玻碳电极被构建，用于灵敏、便捷地电化学检测 1-羟基芘（1-OHP）。该石墨烯修饰电极是通过玻碳电极上电还原氧化石墨烯制备得到的。在石墨烯修饰电极上，通过π-π共轭吸附和电化学氧化，1-OHP 协同地得到了富集。详细研究了 l-OHP 在石墨烯修饰玻碳电极上的电化学行为。所开发的方法在 5-300 nM 的范围内对 1-OHP 的测定给出了线性校准曲线（R = 0.997），检测限为 0.84 nM（S/N = 3）。该方法还成功地应用于尿液样品中 l-OHP 的分析，回收率为 97.3-101.1%。
