Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, United States.
Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, United States.
Am J Surg. 2019 Mar;217(3):514-518. doi: 10.1016/j.amjsurg.2018.10.028. Epub 2018 Oct 16.
The aim of this study was to determine whether complications following mastectomy with immediate breast reconstruction (IBR) were associated with breast cancer recurrence.
A retrospective review was performed of women diagnosed with stage I-III breast cancer who underwent mastectomy with IBR between 2005 and 2010. Patient demographics, tumor data, surgical wound complications, treatment details and timing were recorded and analyzed.
We identified 458 women with a median follow up time of 7.6 years. A total of 22% of patients experienced IBR complications. There was a delay in initiation of adjuvant therapy in patients who had a complication (52 vs 41 days, p < 0.001). There was no significant difference in recurrences between groups with and without complications (p = 0.65).
In breast cancer patients who undergo mastectomy with IBR, wound complications delayed initiation of adjuvant systemic therapy, but were not associated with an increased risk of cancer recurrence.
本研究旨在确定即刻乳房重建（IBR）后乳房切除术的并发症是否与乳腺癌复发相关。
对 2005 年至 2010 年间接受乳房切除术伴 IBR 的 I 期至 III 期乳腺癌女性进行回顾性研究。记录并分析了患者的人口统计学、肿瘤数据、手术伤口并发症、治疗细节和时间。
我们共确定了 458 例中位随访时间为 7.6 年的女性患者。IBR 并发症的发生率为 22%。有并发症的患者辅助治疗开始时间延迟（52 天比 41 天，p < 0.001）。有并发症和无并发症组的复发率无显著差异（p = 0.65）。
在接受乳房切除术伴 IBR 的乳腺癌患者中，伤口并发症会延迟辅助全身治疗的开始，但与癌症复发风险增加无关。
