Fleegler E J
Hand Clin. 1987 May;3(2):197-212.
This review can only introduce the subject of tumors found involving the skin of the upper extremity. Many benign masses as well as some malignant tumors have to be considered when a patient calls to the physician's attention a lump, firm area, color change, ulcer, or other alteration in the skin. In response, the physician must have a high index of suspicion, take a careful history, and carry out a thorough examination in order to develop a safe approach. Thought has to be given to the complex anatomy of this area. Understanding of the pathophysiology of tumors and of possible later additional therapy is needed to plan an appropriate biopsy. In the brief discussions of treatment, the difficulty in choosing margins of resection and assessing the efficacy of lymph node dissection is mentioned. An open mind and assessment of future reports of studies in progress may be helpful. Whatever treatment is applied to the malignant tumors under consideration, it is my opinion that one must persist in this until one obtains tumor-free margins. The surgeon undertaking this responsibility must apply the same tumor techniques including operating room discipline that would be applied to any serious malignancy. Consultation and careful work with colleagues that are able to assess the potential for response to chemotherapy, immunotherapy, and/or radiotherapy, should be sought. Subtle hazards in our environment, such as changing risk of sun exposure, industrial chemicals, and irradiation should be pointed out to our patients. These are a challenge to the student of this subject, just as tobacco products are to those involved with malignancies of the head and neck, respiratory, and other systems. All of the previously mentioned methods must be used in the anatomically complex upper extremity to preserve function while ridding the patient of the burden of a disfiguring or painful benign process, or even a life-threatening malignancy.
本综述仅介绍发现累及上肢皮肤的肿瘤这一主题。当患者向医生指出皮肤上有肿块、硬结区域、颜色改变、溃疡或其他变化时,必须考虑许多良性肿块以及一些恶性肿瘤。作为回应,医生必须保持高度的怀疑指数,仔细询问病史,并进行全面检查,以便制定出安全的治疗方法。必须考虑到该区域复杂的解剖结构。为了计划合适的活检,需要了解肿瘤的病理生理学以及可能的后续附加治疗。在简短的治疗讨论中,提到了选择切除边缘和评估淋巴结清扫疗效的困难。保持开放的心态并评估正在进行的研究的未来报告可能会有所帮助。无论对所考虑的恶性肿瘤采用何种治疗方法,我认为必须坚持下去,直到获得无肿瘤边缘。承担此责任的外科医生必须应用与治疗任何严重恶性肿瘤相同的肿瘤治疗技术,包括手术室规范。应寻求能够评估化疗、免疫治疗和/或放疗反应潜力的同事的咨询并与其密切合作。应向我们的患者指出我们环境中的细微危害,例如阳光照射风险的变化、工业化学品和辐射。这些对该领域的学生来说是一项挑战,就像烟草制品对涉及头颈部、呼吸及其他系统恶性肿瘤的人来说是一项挑战一样。在解剖结构复杂的上肢,必须使用上述所有方法来保留功能,同时消除患者因毁容性或疼痛性良性病变甚至危及生命的恶性肿瘤所带来的负担。