Addo Ntim Susana, Norris Samuel, Goodwin David G, Breffke Jens, Scott Keana, Sung Lipiin, Thomas Treye A, Noonan Gregory O
a Office of Regulatory science, US FDA , Center for Food Safety and Applied Nutrition , College Park , MD , USA.
b Materials Measurement Science Division , National Institute of Standards and Technology , Gaithersburg , MD , USA.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Nov;35(11):2279-2290. doi: 10.1080/19440049.2018.1529437. Epub 2018 Oct 23.
Migration evaluation involving nano-enabled food contact materials (FCMs) mostly focuses on potential nanoparticle release from new unused products. This may not represent consumer use practices encountered by the FCMs in their lifecycle. In order to determine if product use impacts the release of nanoparticles or other FCM components, it is necessary to perform migration evaluations under typical consumer use scenarios. A quantitative assessment of nanoparticle release from a commercially available nanosilver-enabled cutting board was performed under five conditions intended to simulate consumer use. Knife motion, washing and scratching scenarios were simulated by linear abrasion using knife blades, scrubbing pads and tungsten carbide burr attachments, respectively. Migration was evaluated using water and 3% acetic acid as food simulants. Low concentrations of silver (Ag) were detected in water simulants, a small portion (<4 ng dm) in the form of silver nanoparticles (AgNPs) with particle number concentrations on the order of 10 particles dm. Median particle diameter was 40 nm. Nanoparticle release into water was observed under all five consumer use scenarios studied, however there was no correlation with the different levels of stress simulated.
