University of Washington School of Medicine, Seattle, Washington.
Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, Washington.
J Clin Sleep Med. 2018 Oct 15;14(10):1645-1652. doi: 10.5664/jcsm.7364.
Poor adherence undermines the effectiveness of positive airway pressure (PAP) therapy for sleep apnea. Disparities exist in PAP adherence by race/ethnicity and neighborhood socioeconomic status (SES), but the etiology of these differences is poorly understood. We investigated whether home environmental factors contribute to PAP adherence and whether identified factors explain disparities in adherence by SES.
Adult patients with sleep apnea were surveyed at clinic visits about their sleep environment. Medical records were abstracted for demographic data, sleep apnea severity, comorbidities, and objective PAP adherence. We evaluated the association between aspects of home sleep environment with PAP adherence using multivariate linear and logistic regression, and assessed effect modification by SES factors.
Participants (n = 119) were diverse, with 44% nonwhite and 35% uninsured/Medicaid. After adjusting for age, sex, race/ethnicity, insurance, neighborhood SES, education, and marital status, participants who endorsed changing sleeping location once per month or more (18%, n = 21) had 77% lower odds of meeting PAP adherence criteria (> 4 h/night for 70% of nights) and less PAP use (median -11 d/mo, 95% confidence intervals -15.3, -6.5). Frequency of sleeping location change was the only environmental factor surveyed associated with PAP adherence.
Frequent change in sleeping location is associated with reduced PAP adherence, independent of sociodemographic factors. This novel finding has implications for physician-patient dialogue. PAP portability considerations in device selection and design may modify adherence and potentially improve treatment outcomes. Prospective investigation is needed to confirm this finding and inform design of possible interventions.
不良的依从性会降低正压通气(PAP)治疗睡眠呼吸暂停的疗效。种族/民族和社区社会经济地位(SES)的 PAP 依从性存在差异,但这些差异的病因知之甚少。我们调查了家庭环境因素是否会影响 PAP 依从性,以及确定的因素是否可以解释 SES 差异对依从性的影响。
在就诊时,对患有睡眠呼吸暂停的成年患者进行睡眠环境调查。从病历中提取人口统计学数据、睡眠呼吸暂停严重程度、合并症和客观 PAP 依从性数据。我们使用多元线性和逻辑回归评估家庭睡眠环境各方面与 PAP 依从性的关联,并评估 SES 因素的调节作用。
参与者(n = 119)具有多样性,其中 44%是非白人,35%没有保险/医疗补助。在调整年龄、性别、种族/民族、保险、社区 SES、教育程度和婚姻状况后,每月或更多次改变睡眠地点的参与者(18%,n = 21)符合 PAP 依从性标准(每晚 4 小时或更长时间,70%的时间)的可能性降低了 77%,并且 PAP 使用量更少(中位数-11 天/月,95%置信区间-15.3,-6.5)。睡眠地点改变频率是唯一与 PAP 依从性相关的环境因素。
频繁改变睡眠地点与 PAP 依从性降低有关,独立于社会人口因素。这一新发现对医患对话具有启示意义。在设备选择和设计中考虑 PAP 的便携性可能会改变依从性,并有可能改善治疗结果。需要进行前瞻性研究来证实这一发现,并为可能的干预措施提供信息。