Wallace Douglas M, Sawyer A M, Shafazand S
Department of Neurology, Sleep Medicine Division, University of Miami Miller School of Medicine, Miami, FL, USA.
Neurology Service, Bruce W. Carter Department of Veterans Affairs Medical Center, 1201 NW 16th Street, Miami, FL, 33125, USA.
Sleep Breath. 2018 Mar;22(1):5-15. doi: 10.1007/s11325-017-1605-3. Epub 2018 Jan 4.
There is limited information on the association between pre-treatment insomnia symptoms and dysfunctional sleep beliefs with continuous positive airway pressure (CPAP) adherence in veterans with obstructive sleep apnea (OSA). Our aims were to describe demographic and sleep characteristics of veterans with and without comorbid insomnia and determine whether pre-treatment insomnia symptoms and dysfunctional sleep beliefs predict CPAP use after 6 months of therapy.
Hispanic veterans attending the Miami VA sleep clinic were recruited and completed the insomnia severity index, the dysfunctional sleep belief and attitude scale (DBAS), and other questionnaires. Participants were asked to return after 7 days and 1 and 6 months to repeat questionnaires and for objective CPAP adherence download. Hierarchical regression models were performed to determine adjusted associations of pre-treatment insomnia symptoms and DBAS sub-scores on 6-month mean daily CPAP use.
Fifty-three participants completed the 6-month follow-up visit with a mean CPAP use of 3.4 ± 1.9 h. Veterans with comorbid insomnia had lower mean daily CPAP use (168 ± 125 vs 237 ± 108 min, p = 0.04) and lower percent daily CPAP use ≥ 4 h (32 ± 32 vs 51 ± 32%, p = 0.05) compared to participants without insomnia. In adjusted analyses, pre-treatment insomnia symptoms (early, late, and aggregated nocturnal symptoms) and sleep dissatisfaction were predictive of lower CPAP use at 6 months. Pre-treatment dysfunctional sleep beliefs were not associated with CPAP adherence.
Pre-treatment nocturnal insomnia symptoms and sleep dissatisfaction predicted poorer 6- month CPAP use. Insomnia treatment preceding or concurrent with CPAP initiation may eliminate a barrier to regular use.
关于阻塞性睡眠呼吸暂停(OSA)退伍军人治疗前失眠症状和功能失调性睡眠信念与持续气道正压通气(CPAP)依从性之间的关联,相关信息有限。我们的目的是描述合并或未合并失眠的退伍军人的人口统计学和睡眠特征,并确定治疗前失眠症状和功能失调性睡眠信念是否能预测治疗6个月后CPAP的使用情况。
招募到迈阿密退伍军人事务部睡眠诊所就诊的西班牙裔退伍军人,他们完成了失眠严重程度指数、功能失调性睡眠信念与态度量表(DBAS)及其他问卷。参与者被要求在7天、1个月和6个月后返回,以重复填写问卷并进行CPAP客观依从性数据下载。采用分层回归模型来确定治疗前失眠症状和DBAS子分数与6个月平均每日CPAP使用情况之间的校正关联。
53名参与者完成了为期6个月的随访,平均CPAP使用时间为3.4±1.9小时。与未患失眠的参与者相比,合并失眠的退伍军人平均每日CPAP使用时间较短(168±125分钟 vs 237±108分钟,p = 0.04),每日CPAP使用时间≥4小时的百分比也较低(32±32% vs 51±32%,p = 0.05)。在校正分析中,治疗前失眠症状(早期、晚期和夜间综合症状)及睡眠不满意可预测6个月时CPAP使用时间较短。治疗前功能失调性睡眠信念与CPAP依从性无关。
治疗前夜间失眠症状和睡眠不满意预示着6个月时CPAP使用情况较差。在开始CPAP治疗之前或同时进行失眠治疗可能会消除规律使用CPAP的障碍。