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阻塞性睡眠呼吸暂停退伍军人在持续气道正压通气治疗依从性方面的种族差异。

Racial disparities in positive airway pressure therapy adherence among veterans with obstructive sleep apnea.

作者信息

Hsu Nancy, Zeidler Michelle R, Ryden Armand M, Fung Constance H

机构信息

Scripps Health, San Diego, California.

Veterans Affairs Greater Los Angeles Healthcare, Los Angeles, California.

出版信息

J Clin Sleep Med. 2020 Aug 15;16(8):1249-1254. doi: 10.5664/jcsm.8476.

Abstract

STUDY OBJECTIVES

Black individuals are disproportionately affected by diabetes, cardiovascular disease, obesity, and OSA. Adherence to PAP therapy has been reported to be lower among black individuals. This study seeks to examine associations between black race and PAP adherence among veterans with OSA.

METHODS

This was a retrospective study. Veterans newly diagnosed with OSA at a single Department of Veterans Affairs sleep center who were prescribed a modem-enabled PAP device between January 2015 and November 2017 were enrolled. PAP adherence was defined as ≥ 4 hours nightly usage for at least 70% of nights measured at 30 days from PAP setup. We examined the relationship between race and adherence, controlling for sex, marital status, age, socioeconomic status, residual apnea-hypopnea index), and mask leak.

RESULTS

Of 3013 patients identified with OSA, 2571 (85%) were newly started on PAP therapy (95% male, aged 59 years ± 14 years, 45% married, 8% with neighborhood socioeconomic disadvantage). Twenty-five percent of participants were black, and 57% were white. PAP adherence at 30 days was 50% overall (42% among blacks, 53% among nonblacks). Black race was associated with reduced 30-day PAP adherence in unadjusted (P < .001) and adjusted logistic regression models (odds ratio = 0.64; 95% CI, 0.53 - 0.78; P < .001).

CONCLUSIONS

Among veterans with OSA, black race was associated with reduced PAP adherence. These findings suggest health inequality among black individuals in the treatment of OSA.

摘要

研究目的

黑人在糖尿病、心血管疾病、肥胖症和阻塞性睡眠呼吸暂停(OSA)方面受到的影响尤为严重。据报道,黑人对持续气道正压通气(PAP)治疗的依从性较低。本研究旨在探讨黑人种族与OSA退伍军人PAP治疗依从性之间的关联。

方法

这是一项回顾性研究。纳入2015年1月至2017年11月期间在单一退伍军人事务部睡眠中心新诊断为OSA并被处方了支持调制解调器的PAP设备的退伍军人。PAP治疗依从性定义为从PAP设备设置起30天内,至少70%的夜晚每晚使用时间≥4小时。我们研究了种族与依从性之间的关系,并对性别、婚姻状况、年龄、社会经济地位、残余呼吸暂停低通气指数和面罩漏气进行了控制。

结果

在3013名确诊为OSA的患者中,2571名(85%)开始接受PAP治疗(95%为男性,年龄59岁±14岁,45%已婚,8%所在社区存在社会经济劣势)。25%的参与者为黑人,57%为白人。30天时PAP治疗的总体依从率为50%(黑人中为42%,非黑人中为53%)。在未调整(P<.001)和调整后的逻辑回归模型中,黑人种族与30天PAP治疗依从性降低相关(比值比=0.64;95%可信区间,0.53 - 0.78;P<.001)。

结论

在患有OSA的退伍军人中,黑人种族与PAP治疗依从性降低相关。这些发现表明黑人在OSA治疗中存在健康不平等。

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