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儿童双侧视神经病变伴中枢性尿崩症。

Bilateral optic neuropathy with central diabetes insipidus in a child.

机构信息

Department of Neuro Ophthalmology and Pediatric Ophthalmology, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Sankara Nethralaya and VRR Scans, Chennai, Tamil Nadu, India.

出版信息

Indian J Ophthalmol. 2018 Nov;66(11):1642-1644. doi: 10.4103/ijo.IJO_281_18.

Abstract

Central nervous system germ cell tumors are rare and they occur in the first two decades of life. Optic nerve germinomas can sometimes mimic optic nerve inflammation. In this case report, we discuss an 11-year-old girl who presented with features of presumed bilateral optic neuritis and developed polyuria and polydipsia, subsequently she was diagnosed to have infiltrative etiology. Her clinical and radiological presentations were initially consistent with inflammatory optic neuropathy. Poor visual recovery to steroid therapy and progressive visual loss warranted the need for optic nerve biopsy which revealed germinoma.

摘要

中枢神经系统生殖细胞肿瘤较为罕见,通常发生于生命的前 20 年。视神经胚细胞瘤有时可能类似于视神经炎症。在本病例报告中,我们讨论了一位 11 岁女孩,其最初表现为双侧视神经炎的特征,并出现多尿和多饮,随后被诊断为浸润性病因。她的临床和影像学表现最初与炎症性视神经病变一致。类固醇治疗效果不佳且视力持续下降,需要进行视神经活检,活检结果显示为生殖细胞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c122/6213697/202aecafe58b/IJO-66-1642-g001.jpg

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