Department of Orthopaedic Surgery, Nihon University Itabashi Hospital, 30-1 Oyaguchikamimati Itabashi-ku, Tokyo 173-8610, Japan.
Biomed Res Int. 2018 Sep 25;2018:5785708. doi: 10.1155/2018/5785708. eCollection 2018.
The purpose of this study was to evaluate the durability and biological response of a new Posterior Dynamic Stabilization system using polyethylene with vitamin E on the sliding surface.
The use of polyethylene with vitamin E on the sliding surface in Posterior Dynamic Stabilization has not been reported previously.
A developed pedicle screw-based Posterior Dynamic system consists of four parts: a set screw, a rod, a ball, and a pedicle screw. The rod is inserted into the through hole of the ball, and the ball is sandwiched by the set screw. . Testing was conducted under a dynamic compressive load of 50N at a speed of 1 Hz for 1 million cycles. We examined the loss of polyethylene due to abrasion in 3 units. . In two pigs, a new pedicle screw and a conventional pedicle screw were inserted in L2 and L3/4, and L4 and L2/3, respectively. After breeding for 6 months, autopsies were performed. CT imaging was used to evaluate bone union of the facet joint. Abrasive specimens were prepared, and abrasion powder and inflammatory cell infiltration were evaluated microscopically.
The average loss of polyethylene due to abrasion was -0.01 mg. In all units, polyethylene showed a decrease of 0.1 mm or less at the contact point with the set screw. The facet joints between the conventional screws exhibited bone fusion, but the facet joint between the conventional and the new screw retained mobility with no bony fusion. No abrasion powder was found and inflammatory cell infiltration was only minimally observed.
The new Posterior Dynamic Stabilization system exhibited a high level of durability and biological safety.
本研究旨在评估新型聚乙烯维生素 E 滑动面后路动态稳定系统的耐用性和生物反应。
此前尚未有后路动态稳定中使用聚乙烯维生素 E 滑动面的报道。
一种新型基于椎弓根螺钉的后路动态系统由四个部分组成：一组螺钉、一根杆、一个球和一个椎弓根螺钉。杆插入球的通孔中，球由一组螺钉夹住。在 50N 的动态压缩负荷下，以 1Hz 的速度进行 100 万次循环测试。我们在 3 个单位中检查了磨损引起的聚乙烯丢失情况。在 2 只猪中，分别在 L2 和 L3/4、L4 和 L2/3 处插入新型椎弓根螺钉和传统椎弓根螺钉。饲养 6 个月后进行尸检。使用 CT 成像评估小关节的骨融合情况。制备磨蚀标本，显微镜下评估磨蚀粉末和炎症细胞浸润情况。
平均磨损导致的聚乙烯丢失为-0.01mg。在所有单位中，与螺钉接触点的聚乙烯减少了 0.1mm 或更少。传统螺钉的小关节显示出骨融合，但传统和新型螺钉之间的小关节保持活动度，没有骨融合。未发现磨蚀粉末，炎症细胞浸润也仅轻微观察到。
新型后路动态稳定系统具有较高的耐用性和生物安全性。
