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[强直性脊柱炎神经根脊髓及神经肌肉并发症的批判性研究]

[Critical study of radiculomedullary and neuromuscular complications of ankylosing spondylitis].

作者信息

Serratrice G, Acquaviva P, Pouget J, Guerra L

出版信息

Rev Rhum Mal Osteoartic. 1987 Mar;54(3):221-7.

PMID:3035702
Abstract

Medullo-radicular and neuro-muscular involvements of ankylosing spondylarthritis, often reported in an analytic fashion in the literature, deserve to be the subject of a critical study. Various neurological manifestations secondary to exceptional atlo-occipital and sometimes axis-atlas subluxations and medullary lesions as well as syndromes of the cauda equina. The medullary lesions have an epidural origin (3 cases in the literature, 2 cases from the authors) or are secondary to a spondylodiscitis (4 cases in the literature) or secondary to both (1 case reported by the authors). As for syndromes of the cauda equina the authors report 3 cases to be added to the 55 published previously. It concerns always old spondylarthritis. The lesions combine posterior diverticula and lesions of the lamina. The treatment is usually ineffective. A special case is represented by forms with trophic disorders. More debatable are the radicular lesions, which, except for intercostal pain, should be linked to local pain. Electromyographic abnormalities are of no significance. Alterations of the paravertebral muscles viewed on the scanner X have, for now, an uncertain significance. Finally, various associations, without significance such as multiple sclerosis, diffuse muscular lesions and the classic spondylotic pseudo-tabes, should be rejected.

摘要

强直性脊柱炎的脊髓神经根及神经肌肉受累情况,在文献中常以分析的方式报道,值得进行批判性研究。存在各种继发于罕见的寰枕关节及有时枢椎 - 寰椎半脱位和脊髓病变以及马尾综合征的神经学表现。脊髓病变有硬膜外起源(文献中有3例,作者报道2例)或继发于脊椎椎间盘炎(文献中有4例)或两者皆有(作者报道1例)。至于马尾综合征,作者报道了3例,需补充到之前已发表的55例中。这些病例均为陈旧性脊柱关节炎。病变包括后部憩室和椎板病变。治疗通常无效。以伴有营养障碍的形式为例外情况。更具争议的是神经根病变,除肋间疼痛外,应与局部疼痛相关。肌电图异常无意义。目前,X线扫描显示的椎旁肌肉改变意义尚不明确。最后,各种无意义的关联,如多发性硬化、弥漫性肌肉病变和典型的脊椎性假脊髓痨,应予以排除。

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