Sheikh Abu Baker, Afzal Rao M, Sagheer Shazib, Bukhari Marvi M, Javed Anam, Nasrullah Adeel, Tariq Usman, Athar Fahad, Saleem Muhammad Sabih
Internal Medicine, University of New Mexico, Albuquerque, USA.
Internal Medicine, Shifa College of Medicine, Islamabad, PAK.
Cureus. 2018 Aug 21;10(8):e3174. doi: 10.7759/cureus.3174.
Osmotic demyelination syndrome is classically associated with a swift adjustment of previously low serum sodium levels which lead to cellular dehydration and subsequent neurological insult. We also review the epidemiology, different postulations to explain the underlying pathophysiology, current diagnostic modalities, subsequent therapeutic interventions used to manage this phenomenon, and the resultant prognosis of this ailment.
渗透性脱髓鞘综合征通常与先前低血清钠水平的快速调整有关，这会导致细胞脱水及随后的神经损伤。我们还回顾了其流行病学、用于解释潜在病理生理学的不同假说、当前的诊断方法、用于处理这一现象的后续治疗干预措施以及这种疾病的最终预后。
