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[小细胞支气管癌局限期的联合放化疗。高剂量放疗后的结果]

[Combination radiochemotherapy in the limited-disease stage of small-cell bronchial carcinoma. Results following high-dosage radiotherapy].

作者信息

Hörmann M, Hackl A, Ranner G, Pongratz M

出版信息

Strahlenther Onkol. 1987 May;163(5):292-6.

PMID:3035733
Abstract

From 1980 through 1984, 72 patients with small cell bronchial carcinomas were treated by radiotherapy. Twenty-one patients who were in a limited disease stage (LD) received chemotherapy according to the ACO scheme and high-dose radiotherapy with 50 Gy. These patients had a complete remission rate of 67% and a partial remission rate of 33%. The median control period was 37 months. At the time of diagnosis, patients had a median survival time of ten months (six to 36 months). A recurrence in the irradiated region was seen in none of the patients, however, 14% of patients developed a recurrence beyond the irradiation field. The results are compared to literature and discussed.

摘要

从1980年到1984年,72例小细胞支气管癌患者接受了放射治疗。21例处于疾病局限期(LD)的患者按照ACO方案接受了化疗以及50 Gy的高剂量放射治疗。这些患者的完全缓解率为67%,部分缓解率为33%。中位控制期为37个月。在诊断时,患者的中位生存时间为10个月(6至36个月)。所有患者均未出现照射区域复发,然而,14%的患者在照射野之外出现了复发。将结果与文献进行了比较并展开讨论。

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