小鼠胸腺中原始细胞的超微结构放射自显影研究。对放射性白血病研究的意义。
Ultrastructural autoradiographic study of blast cells in the mouse thymus. Interest for radioleukemia research.
作者信息
Boniver J, Simar L J, Courtoy R, Betz E H
出版信息
Experientia. 1977 Nov 15;33(11):1505-6. doi: 10.1007/BF01918837.
PMID:303575
Abstract
Ultrastructural autoradiographic studies of mouse thymic blast cells after H3 Tdr injection show that their fine nuclear structure is related to their position in the cell cycle. The variations in the composition of the subcapsular blast cell population during radiation-induced leukemogenesis indicate kinetic changes in thymic lymphopoiesis, which are probably due to the oncogenic process.
摘要
对注射H3 Tdr后小鼠胸腺母细胞进行超微结构放射自显影研究表明，其精细的核结构与其在细胞周期中的位置有关。辐射诱导白血病发生过程中被膜下母细胞群体组成的变化表明胸腺淋巴细胞生成存在动力学变化，这可能是由致癌过程引起的。
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